Tizanidine
- Generic Name
- Tizanidine
- Brand Names
- Zanaflex
- Drug Type
- Small Molecule
- Chemical Formula
- C9H8ClN5S
- CAS Number
- 51322-75-9
- Unique Ingredient Identifier
- 6AI06C00GW
- Background
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition.
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- Indication
Tizanidine is indicated for the relief of muscle spasticity, which can interfere with daily activities. The general recommendation is to reserve tizanidine use for periods of time when there is a particular need for relief, as it has a short duration of action .
- Associated Conditions
- Acute Low Back Pain, Drug Withdrawal Headache, Insomnia, Migraine, Pain, Seizures, Spasticity, Muscle
- Associated Therapies
- Withdrawal From Addictive Substance; Detoxification
A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial
- First Posted Date
- 2013-04-24
- Last Posted Date
- 2021-03-23
- Lead Sponsor
- Acorda Therapeutics
- Target Recruit Count
- 136
- Registration Number
- NCT01839279
- Locations
- 🇺🇸
Covance- Dallas, Dallas, Texas, United States
Bioequivalence Study of Tizanidine HCl Tablets 4 mg of Dr.Reddys Under Fasting Conditions
- First Posted Date
- 2010-06-17
- Last Posted Date
- 2012-01-13
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 42
- Registration Number
- NCT01146028
- Locations
- 🇨🇦
Anapharm Inc., Sainte-Foy (Quebec), Canada
Bioequivalence Study of Tizanidine HCl 4mg Tablets of Dr.Reddy's Under Fed Conditions
- First Posted Date
- 2010-02-10
- Last Posted Date
- 2010-02-10
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 24
- Registration Number
- NCT01065987
- Locations
- 🇨🇦
Anapharm Inc., Sainte-Foy (Quebec), Canada
Drug Development Updates
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