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Procainamide

Generic Name
Procainamide
Brand Names
Procan
Drug Type
Small Molecule
Chemical Formula
C13H21N3O
CAS Number
51-06-9
Unique Ingredient Identifier
L39WTC366D
Background

A derivative of procaine with less CNS action.

Indication

For the treatment of life-threatening ventricular arrhythmias.

Associated Conditions
Supraventricular Arrhythmias, Ventricular Tachycardia (VT), Life-threatening ventricular arrhythmias, Pre-excited atrial fibrillation
Clinical Trials
Related News

RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency Department

Phase 4
Completed
Conditions
Atrial Fibrillation
Interventions
First Posted Date
2020-07-24
Last Posted Date
2025-04-10
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
350
Registration Number
NCT04485195
Locations
🇨🇦

University of Alberta Hospital, Edmonton, Alberta, Canada

🇨🇦

Vancouver General Hospital, Vancouver, British Columbia, Canada

🇨🇦

Montreal Heart Institute, Montreal, Quebec, Canada

and more 11 locations

Prevention of Post-Operative Cardiac Arrhythmias

Phase 4
Conditions
Cardiac; Dysrhythmia, Postoperative
Congenital Heart Surgery
Interventions
First Posted Date
2020-01-21
Last Posted Date
2022-03-15
Lead Sponsor
Jeffrey Moak
Target Recruit Count
870
Registration Number
NCT04234906

Acute Mechanical Response to Anti-arrhythmic Drug Therapy

Not Applicable
Withdrawn
Conditions
Arrhythmias
Interventions
First Posted Date
2015-10-14
Last Posted Date
2018-06-28
Lead Sponsor
Evan Adelstein, MD
Registration Number
NCT02575534
Locations
🇺🇸

Evan Adelstein, Pittsburgh, Pennsylvania, United States

ST-segment Elevation as an AF Endophenotype

Not Applicable
Completed
Conditions
Atrial Fibrillation
Interventions
First Posted Date
2010-09-20
Last Posted Date
2018-05-02
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
161
Registration Number
NCT01205529
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias

Phase 4
Completed
Conditions
Atrial Fibrillation
Tachycardia, Ventricular
Brugada Syndrome
Interventions
First Posted Date
2008-06-20
Last Posted Date
2010-12-15
Lead Sponsor
Hospital Clinic of Barcelona
Target Recruit Count
123
Registration Number
NCT00702117
Locations
🇪🇸

Hospital Puerta de Hierro, Madrid, Spain

🇪🇸

Hospital Donostia, Donostia, Guipuzcoa, Spain

🇪🇸

Hospital La Fe, Valencia, Spain

and more 1 locations

Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)

Phase 3
Completed
Conditions
Atrial Fibrillation
Cardiovascular Diseases
Arrhythmia
Heart Diseases
First Posted Date
1999-10-28
Last Posted Date
2016-03-25
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000556

Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)

Phase 3
Completed
Conditions
Arrhythmia
Cardiovascular Diseases
Heart Arrest
Heart Diseases
Myocardial Infarction
Ventricular Fibrillation
First Posted Date
1999-10-28
Last Posted Date
2013-07-29
Lead Sponsor
University of Washington
Registration Number
NCT00000464

Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)

Phase 3
Completed
Conditions
Heart Diseases
Cardiovascular Diseases
Arrhythmia
Ventricular Fibrillation
Death, Sudden, Cardiac
Tachycardia, Ventricular
Ventricular Arrhythmia
First Posted Date
1999-10-28
Last Posted Date
2016-01-21
Lead Sponsor
University of Utah
Registration Number
NCT00000518
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