Salbutamol

Generic Name
Salbutamol
Brand Names
Airomir, Airsupra, Combivent, Proair, Proventil, Ventolin
Drug Type
Small Molecule
Chemical Formula
C13H21NO3
CAS Number
18559-94-9
Unique Ingredient Identifier
QF8SVZ843E
Background

Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and...

Indication

Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known t...

Associated Conditions
Asthma, Asthmatic Bronchitis, Bronchial Asthma, Bronchoconstriction, Bronchospasm, Chronic Asthma, Chronic Bronchitis, Cough, Emphysema, Exacerbation of asthma, Exercise-Induced Bronchospasm, Hyperkalemia, Wheezing, Excess mucus or phlegm
Associated Therapies
Airway secretion clearance therapy, Bronchodilation

Effect of Nebulized Bronchodilators on Heart Rate

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-06-28
Last Posted Date
2015-10-23
Lead Sponsor
Fahim Khorfan, MD
Target Recruit Count
89
Registration Number
NCT01151579
Locations
🇺🇸

Genesys Regional Medical Center, Grand Blanc, Michigan, United States

Characterization of Placebo Responses in Stable Asthma

First Posted Date
2010-06-14
Last Posted Date
2017-03-30
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
39
Registration Number
NCT01143688
Locations
🇺🇸

Brigham & women's Hospital, Boston, Massachusetts, United States

Comparative Study on the Efficacy and Safety of Procaterol Versus Salbutamol Given Via Metered Dose Inhaler With Spacer in the Management of Acute Asthma Attack in the Emergency Room

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-03-24
Last Posted Date
2010-03-24
Lead Sponsor
Otsuka Pharmaceutical, Inc., Philippines
Target Recruit Count
96
Registration Number
NCT01091337
Locations
🇵🇭

Philippine General Hospital, Manila, Philippines

Bronchodilator Responsiveness in Healthy Young Adults Using Forced Oscillations Technique (FOT)

Not Applicable
Completed
Conditions
First Posted Date
2010-02-11
Last Posted Date
2011-01-19
Lead Sponsor
University of Patras
Target Recruit Count
100
Registration Number
NCT01067534
Locations
🇬🇷

University Hospital of Patras, Patras, Greece

Dose-response of Albuterol in Asthmatics

Phase 4
Completed
Conditions
First Posted Date
2009-07-17
Last Posted Date
2015-05-05
Lead Sponsor
Nemours Children's Clinic
Target Recruit Count
81
Registration Number
NCT00940927
Locations
🇺🇸

Nemours Children's Clinic, Jacksonville, Florida, United States

Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-06-02
Last Posted Date
2009-06-02
Lead Sponsor
University Hospital, Antwerp
Target Recruit Count
6
Registration Number
NCT00911651
Locations
🇧🇪

Antwerp University Hospital, Antwerp, Belgium

Rapid Onset Action of Salbutamol Versus Formoterol

First Posted Date
2009-05-13
Last Posted Date
2009-05-13
Lead Sponsor
All India Institute of Medical Sciences, New Delhi
Target Recruit Count
78
Registration Number
NCT00900874
Locations
🇮🇳

AIIMS, New Delhi, India

Role of Airway Hyperresponsiveness on Performance in Elite Swimmers.

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2009-04-06
Last Posted Date
2013-05-13
Lead Sponsor
Laval University
Target Recruit Count
57
Registration Number
NCT00876135
Locations
🇨🇦

Institut Universitaire de cardiologie et de pneumologie de Québec, Québec, Quebec, Canada

Study Comparing Foster Efficacy Maintenance and Reliever Versus Foster Maintenance + Salbutamol Reliever in Asthmatics

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-03-16
Last Posted Date
2017-03-30
Lead Sponsor
Chiesi Farmaceutici S.p.A.
Target Recruit Count
2079
Registration Number
NCT00861926
Locations
🇮🇹

Pr Papi, Ferrara, Italy

Symbicort Onset of Action 2

First Posted Date
2008-03-28
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
48
Registration Number
NCT00646009
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