Salbutamol

Generic Name
Salbutamol
Brand Names
Airomir, Airsupra, Combivent, Proair, Proventil, Ventolin
Drug Type
Small Molecule
Chemical Formula
C13H21NO3
CAS Number
18559-94-9
Unique Ingredient Identifier
QF8SVZ843E
Background

Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and...

Indication

Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known t...

Associated Conditions
Asthma, Asthmatic Bronchitis, Bronchial Asthma, Bronchoconstriction, Bronchospasm, Chronic Asthma, Chronic Bronchitis, Cough, Emphysema, Exacerbation of asthma, Exercise-Induced Bronchospasm, Hyperkalemia, Wheezing, Excess mucus or phlegm
Associated Therapies
Airway secretion clearance therapy, Bronchodilation
Clinical Trials
Related News

Nebulized Albuterol for Congestive Heart Failure Exacerbation

Phase 2
Withdrawn
Conditions
Congestive Heart Failure
Interventions
Drug: Normal Saline
Drug: Albuterol
First Posted Date
2011-06-17
Last Posted Date
2013-10-10
Lead Sponsor
University of California, San Francisco
Registration Number
NCT01375361
Locations
🇺🇸

University of California, San Francisco, California, United States

Salbutamol Tolerance Onset

Phase 4
Completed
Conditions
Asthma
Interventions
Drug: salbutamol
Drug: Placebo
First Posted Date
2011-04-19
Last Posted Date
2012-07-20
Lead Sponsor
University of Saskatchewan
Target Recruit Count
15
Registration Number
NCT01338311
Locations
🇨🇦

University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma

First Posted Date
2011-03-11
Last Posted Date
2017-06-08
Lead Sponsor
Sanofi
Target Recruit Count
104
Registration Number
NCT01312961
Locations
🇺🇸

Investigational Site Number 840003, Minneapolis, Minnesota, United States

🇺🇸

Investigational Site Number 840006, Saint Louis, Missouri, United States

🇺🇸

Investigational Site Number 840047, Anaheim, California, United States

and more 47 locations

A Chronic Obstructive Pulmonary Disease (COPD) Trial Investigating Roflumilast on Safety and Effectiveness in China, Hong Kong and Singapore:

Phase 3
Completed
Conditions
COPD
Interventions
Drug: Roflumilast
Drug: Placebo
Drug: Salbutamol
First Posted Date
2011-03-11
Last Posted Date
2017-02-01
Lead Sponsor
AstraZeneca
Target Recruit Count
626
Registration Number
NCT01313494

A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)

First Posted Date
2011-02-24
Last Posted Date
2012-06-22
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
306
Registration Number
NCT01302587
Locations
🇺🇸

Teva Clinical Study Site 10099, Seattle, Washington, United States

🇺🇸

Teva Clinical Study Site 10090, Indianapolis, Indiana, United States

🇺🇸

Teva Clinical Study Site 10097, Overland Park, Kansas, United States

and more 18 locations

A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol

First Posted Date
2010-12-20
Last Posted Date
2019-01-29
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
48
Registration Number
NCT01263197
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Evansville, Indiana, United States

Respiratory Impedance and Obliterative Bronchiolitis

First Posted Date
2010-12-07
Last Posted Date
2013-01-31
Lead Sponsor
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Target Recruit Count
26
Registration Number
NCT01255449
Locations
🇮🇹

U.O. Medicina Preventiva e del Lavoro, Laboratorio di Fisiopatologia Respiratoria, IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy

Dose Finding Study of Albuterol Sulfate in Patients With Intermittent or Persistent Mild Asthma

First Posted Date
2010-12-03
Last Posted Date
2018-03-13
Lead Sponsor
Acerus Pharmaceuticals Corporation
Registration Number
NCT01252758

Efficacy of Albuterol in the Treatment of Congenital Myasthenic Syndromes

Phase 1
Completed
Conditions
Congenital Myasthenic Syndrome
Interventions
Drug: Albuterol
First Posted Date
2010-09-16
Last Posted Date
2016-01-01
Lead Sponsor
Mayo Clinic
Target Recruit Count
21
Registration Number
NCT01203592
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Optimal Albuterol Regimens for Acute Asthma Exacerbations: DBRCT Pilot Study

Not Applicable
Completed
Conditions
Acute Asthma
Interventions
Drug: Albuterol
First Posted Date
2010-09-08
Last Posted Date
2017-09-29
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
16
Registration Number
NCT01196377
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