Salbutamol

Generic Name
Salbutamol
Brand Names
Airomir, Airsupra, Combivent, Proair, Proventil, Ventolin
Drug Type
Small Molecule
Chemical Formula
C13H21NO3
CAS Number
18559-94-9
Unique Ingredient Identifier
QF8SVZ843E
Background

Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and...

Indication

Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known t...

Associated Conditions
Asthma, Asthmatic Bronchitis, Bronchial Asthma, Bronchoconstriction, Bronchospasm, Chronic Asthma, Chronic Bronchitis, Cough, Emphysema, Exacerbation of asthma, Exercise-Induced Bronchospasm, Hyperkalemia, Wheezing, Excess mucus or phlegm
Associated Therapies
Airway secretion clearance therapy, Bronchodilation

Study Investigating Repeat Doses Of A New Medication (GSK159797) In Asthmatic Patients

First Posted Date
2006-07-31
Last Posted Date
2016-10-28
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
54
Registration Number
NCT00358488
Locations
🇬🇧

GSK Investigational Site, Manchester, United Kingdom

Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients

Phase 4
Completed
Conditions
Interventions
First Posted Date
2006-07-20
Last Posted Date
2011-04-19
Lead Sponsor
Queen's University
Target Recruit Count
12
Registration Number
NCT00354354
Locations
🇨🇦

Respiratory Investigation Unit (Queen's University), Kingston, Ontario, Canada

Viapaed Study In Children And Adolescents With Asthma

First Posted Date
2006-04-19
Last Posted Date
2017-10-19
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
285
Registration Number
NCT00315744
Locations
🇩🇪

GSK Investigational Site, Hamburg, Germany

The Effect of Nebulized Albuterol on Donor Oxygenation

First Posted Date
2006-04-03
Last Posted Date
2018-03-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
506
Registration Number
NCT00310401
Locations
🇺🇸

California Transplant Donor Network, Oakland, California, United States

Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-BAI in Pediatric Asthmatics

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-03-30
Last Posted Date
2022-04-01
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
95
Registration Number
NCT00308685
Locations
🇺🇸

Allergy & Asthma Specialist Medical Group, Huntington Beach, California, United States

🇺🇸

Little Rock Allergy and Asthma, Little Rock, Arkansas, United States

🇺🇸

Allergy & Asthma Associates of Santa Clara Valley Research Center, San Jose, California, United States

and more 9 locations

Effect of Budesonide / Formoterol Combination in Repeated AMP Provocations

Phase 4
Completed
Conditions
First Posted Date
2006-01-09
Last Posted Date
2011-06-01
Lead Sponsor
AstraZeneca
Target Recruit Count
20
Registration Number
NCT00272753
Locations
🇳🇱

Research Site, Groningen, Netherlands

Genetic Determinants of the Response to Salbutamol Among Asthma Patients

Not Applicable
Conditions
First Posted Date
2005-09-13
Last Posted Date
2008-10-29
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
150
Registration Number
NCT00162396
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

Genetic Determinants of the Bronchodilatation Effect of Albuterol ex-Vivo

Not Applicable
Conditions
First Posted Date
2005-09-13
Last Posted Date
2008-10-29
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
150
Registration Number
NCT00162422
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

Treatment of Multiple Sclerosis With Copaxone and Albuterol

First Posted Date
2002-06-20
Last Posted Date
2016-09-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
40
Registration Number
NCT00039988
Locations
🇺🇸

Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States

Study of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD)

Not Applicable
Completed
Conditions
First Posted Date
2001-12-07
Last Posted Date
2015-03-25
Lead Sponsor
FDA Office of Orphan Products Development
Target Recruit Count
160
Registration Number
NCT00027391
Locations
🇺🇸

Ohio State University Medical Center, Columbus, Ohio, United States

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