Tramadol
- Generic Name
- Tramadol
- Brand Names
- Conzip, Durela, Qdolo, Ralivia, Ryzolt, Seglentis, Tridural, Ultracet, Ultram, Zytram
- Drug Type
- Small Molecule
- Chemical Formula
- C16H25NO2
- CAS Number
- 27203-92-5
- Unique Ingredient Identifier
- 39J1LGJ30J
- Background
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
- Indication
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
- Associated Conditions
- Acute Pain, Premature Ejaculation, Severe Pain, Acute, moderate, severe Pain, Moderate Pain
- Associated Therapies
- -
Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars
- Conditions
- Interventions
- First Posted Date
- 2024-02-01
- Last Posted Date
- 2024-02-20
- Lead Sponsor
- EMS
- Target Recruit Count
- 252
- Registration Number
- NCT06237231
5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical Trial
- Conditions
- Interventions
- First Posted Date
- 2024-01-31
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 150
- Registration Number
- NCT06232577
- Locations
- 🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy
- Conditions
- Interventions
- First Posted Date
- 2024-01-22
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- Mylan Specialty, LP
- Target Recruit Count
- 408
- Registration Number
- NCT06215820
- Locations
- 🇺🇸
Investigator site 105, San Antonio, Texas, United States
🇺🇸Investigator site 101, Salt Lake City, Utah, United States
🇺🇸Investigator site 112, Miami, Florida, United States
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy
- Conditions
- Interventions
- First Posted Date
- 2024-01-22
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- Mylan Specialty, LP
- Target Recruit Count
- 570
- Registration Number
- NCT06215859
- Locations
- 🇺🇸
Investigator site 219, San Antonio, Texas, United States
🇺🇸Investigator site 202, Anaheim, California, United States
🇺🇸Investigator site 222, Bakersfield, California, United States
Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-12-15
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- Baskent University
- Target Recruit Count
- 45
- Registration Number
- NCT06172920
- Locations
- 🇹🇷
Baskent University Ankara Hospital, Ankara, Turkey
Tramadol and Tramadol Plus Ketamine for Shivering Prevention After Spinal Anesthesia in Lower Segment Caeserian Section
- First Posted Date
- 2023-11-18
- Last Posted Date
- 2023-11-18
- Lead Sponsor
- Ziauddin University
- Target Recruit Count
- 190
- Registration Number
- NCT06134895
- Locations
- 🇵🇰
Muhammad Arif, Karachi, Sindh, Pakistan
Preemptive Oral Gabapentin and Tramadol on Postoperative Pain After Knee Arthroscopy
- Conditions
- Interventions
- First Posted Date
- 2023-11-01
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 50
- Registration Number
- NCT06112223
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
- Conditions
- Interventions
- First Posted Date
- 2023-11-01
- Last Posted Date
- 2024-05-02
- Lead Sponsor
- Damascus University
- Target Recruit Count
- 80
- Registration Number
- NCT06112548
- Locations
- 🇸🇾
Damascus university, Damascus, Syrian Arab Republic
Evaluation of the Efficacy of Regional Anaesthesia for Analgesia After Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2023-08-23
- Last Posted Date
- 2024-08-12
- Target Recruit Count
- 90
- Registration Number
- NCT06008002
- Locations
- 🇹🇷
Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2023-08-16
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- Laboratorios Liomont
- Target Recruit Count
- 58
- Registration Number
- NCT05995912
- Locations
- 🇲🇽
Oaxaca Site Management Organization, Oaxaca, Mexico
Drug Development Updates
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