Buprenorphine
- Generic Name
- Buprenorphine
- Brand Names
- Belbuca, Brixadi, Buprenex, Buprenorphine, Butrans, Sublocade, Suboxone, Subutex, Zubsolv, Buvidal, Sixmo
- Drug Type
- Small Molecule
- Chemical Formula
- C29H41NO4
- CAS Number
- 52485-79-7
- Unique Ingredient Identifier
- 40D3SCR4GZ
- Background
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain. It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1 fixed-dose c...
- Indication
Buprenorphine is available in different formulations, such as sublingual tablets, buccal films, transdermal films, and injections, alone or in combination with naloxone.
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- Associated Conditions
- Opioid Dependence, Severe Pain, Moderate Opioid Dependence, Moderate Pain, Severe Opioid Dependence
- Associated Therapies
- -
Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2020-06-29
- Lead Sponsor
- Yale University
- Registration Number
- NCT00000216
- Locations
- 🇺🇸
APT Residential Services Division, New Haven, Connecticut, United States
Temporal Discounting Delayed Outcomes on Opioid-Dependent Outpatients - 20
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2008-11-20
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000238
- Locations
- 🇺🇸
Treatment Research Center, Burlington, Vermont, United States
IV Cocaine Abuse: A Laboratory Model - 3
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2015-08-31
- Lead Sponsor
- New York State Psychiatric Institute
- Registration Number
- NCT00000214
- Locations
- 🇺🇸
Columbia University, New York, New York, United States
Buprenorphine Maintenance for Opioid Addicts - 3
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2020-04-29
- Lead Sponsor
- Yale University
- Registration Number
- NCT00000204
- Locations
- 🇺🇸
VA Connecticut Healthcare System, New Haven, Connecticut, United States
Combining Behavioral Treatment With Agonist Maintenance - 1
- Conditions
- Interventions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2018-01-17
- Lead Sponsor
- Yale University
- Target Recruit Count
- 168
- Registration Number
- NCT00000311
- Locations
- 🇺🇸
APT Residential Services Division, New Haven, Connecticut, United States
Treatment Efficacy for Drug Abuse and AIDS Prevention - 1
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000210
- Locations
- 🇺🇸
McLean Hospital, Dept. of Psychiatry, Belmont, Massachusetts, United States
Buprenorphine Detox With Two Types of Treatment. BBD II - 11
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2016-05-06
- Lead Sponsor
- University of Vermont
- Registration Number
- NCT00000229
- Locations
- 🇺🇸
Treatment Research Center, Burlington, Vermont, United States
Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2020-07-07
- Lead Sponsor
- Yale University
- Registration Number
- NCT00000319
- Locations
- 🇺🇸
APT Residential Services Division, New Haven, Connecticut, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.