Buprenorphine
- Generic Name
- Buprenorphine
- Brand Names
- Belbuca, Brixadi, Buprenex, Buprenorphine, Butrans, Sublocade, Suboxone, Subutex, Zubsolv, Buvidal, Sixmo
- Drug Type
- Small Molecule
- Chemical Formula
- C29H41NO4
- CAS Number
- 52485-79-7
- Unique Ingredient Identifier
- 40D3SCR4GZ
- Background
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain. It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1 fixed-dose c...
- Indication
Buprenorphine is available in different formulations, such as sublingual tablets, buccal films, transdermal films, and injections, alone or in combination with naloxone.
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- Associated Conditions
- Opioid Dependence, Severe Pain, Moderate Opioid Dependence, Moderate Pain, Severe Opioid Dependence
- Associated Therapies
- -
Assessing the Safety of Buprenorphine in People With Sickle Cell Disease
- First Posted Date
- 2018-04-10
- Last Posted Date
- 2022-04-25
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 47
- Registration Number
- NCT03492099
- Locations
- 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
Feasibility of the Utilization of Buprenorphine in the Emergency Room to Treat Clinical Opioid Withdrawal
- Conditions
- Interventions
- First Posted Date
- 2018-04-05
- Last Posted Date
- 2018-12-13
- Lead Sponsor
- Virginia Commonwealth University
- Target Recruit Count
- 3
- Registration Number
- NCT03489161
- Locations
- 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States
Bariatric Surgery and Pharmacokinetics of Buprenorphine
- Conditions
- First Posted Date
- 2018-03-09
- Last Posted Date
- 2023-03-27
- Lead Sponsor
- Norwegian University of Science and Technology
- Target Recruit Count
- 12
- Registration Number
- NCT03460314
- Locations
- 🇳🇴
St. Olavs University Hospital, Trondheim, Norway
Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair
- First Posted Date
- 2017-12-21
- Last Posted Date
- 2021-04-08
- Lead Sponsor
- Hospital Italiano de Buenos Aires
- Target Recruit Count
- 50
- Registration Number
- NCT03380533
- Locations
- 🇦🇷
Hospital Italiano de Buenos Aires, Buenos Aires, Caba, Argentina
Efficacy of Buprenorphine on Postoperative Endodontic Analgesia
- Conditions
- Interventions
- First Posted Date
- 2017-08-31
- Last Posted Date
- 2019-04-23
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 10
- Registration Number
- NCT03268278
- Locations
- 🇺🇸
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency Department
- First Posted Date
- 2017-08-22
- Last Posted Date
- 2017-10-19
- Lead Sponsor
- Alameda Health System
- Target Recruit Count
- 122
- Registration Number
- NCT03256487
- Locations
- 🇺🇸
Alameda Health System, Highland Hospital, Oakland, California, United States
A Strategy to Improve Success of Treatment Discontinuation in Buprenorphine Responders
- First Posted Date
- 2017-07-28
- Last Posted Date
- 2022-11-07
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 11
- Registration Number
- NCT03232346
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Buprenorphine in the Emergency Department
- Conditions
- Interventions
- First Posted Date
- 2017-06-02
- Last Posted Date
- 2017-06-02
- Lead Sponsor
- St. Joseph's Health Centre Toronto
- Target Recruit Count
- 26
- Registration Number
- NCT03174067
High Dosage Buprenorphine as a Drug Strategy Withdrawal Assistance of Analgesics Opioid
- First Posted Date
- 2017-05-17
- Last Posted Date
- 2021-07-06
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Target Recruit Count
- 60
- Registration Number
- NCT03156907
- Locations
- 🇫🇷
CHU Clermont-Ferrand, Clermont-Ferrand, Auvergne, France
Onsite Buprenorphine Treatment at Syringe Exchange Programs
- Conditions
- Interventions
- First Posted Date
- 2017-05-12
- Last Posted Date
- 2024-04-15
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 98
- Registration Number
- NCT03150173
- Locations
- 🇺🇸
New York Harm Reduction Educators, New York, New York, United States
🇺🇸BOOM!Health Harm Reduction Center, Bronx, New York, United States
🇺🇸Washington Heights CORNER Project, New York, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.