Misoprostol
- Generic Name
- Misoprostol
- Brand Names
- Arthrotec, Cytotec, Mifegymiso
- Drug Type
- Small Molecule
- Chemical Formula
- C22H38O5
- CAS Number
- 59122-46-2
- Unique Ingredient Identifier
- 0E43V0BB57
- Background
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and f...
- Indication
Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients. Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers. Misoprostol is used off label for the manage...
- Associated Conditions
- Gastric Ulcer, Incomplete Abortion, Missed Abortion, Postpartum Haemorrhage (PPH)
- Associated Therapies
- Induction of cervix ripening therapy, Medically induced abortion
Misoprostol for NASH
- First Posted Date
- 2023-04-07
- Last Posted Date
- 2023-04-07
- Lead Sponsor
- Ziauddin University
- Target Recruit Count
- 50
- Registration Number
- NCT05804305
- Locations
- 🇵🇰
Dr. Ziauddin Hospital Clifton, Karachi, Sindh, Pakistan
Preoperative Vaginal Dinoprostone Versus Misoprostone in Abdominal Myomectomy
- First Posted Date
- 2023-03-09
- Last Posted Date
- 2023-03-09
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 90
- Registration Number
- NCT05761418
- Locations
- 🇪🇬
Beni-suef university, Banī Suwayf, Egypt
Prostaglandins Versus Trans-cervical Balloon for Induction of Labor in Fetal Growth Restriction (PROBIN)
- Conditions
- Interventions
- First Posted Date
- 2023-01-06
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- University Hospital, Bordeaux
- Target Recruit Count
- 774
- Registration Number
- NCT05674487
- Locations
- 🇫🇷
CHU Bordeaux, Bordeaux, France
Sublingual Misoprostol in Reduction of Caesarean Blood Loss
- Conditions
- Interventions
- First Posted Date
- 2022-09-08
- Last Posted Date
- 2023-04-12
- Lead Sponsor
- OZORI EBIOGBO STANLEY
- Target Recruit Count
- 152
- Registration Number
- NCT05532215
- Locations
- 🇳🇬
Federal Medical Centre Yenagoa, Yenagoa, Bayelsa, Nigeria
MISOBEST - Orally Misoprostol Solution (Cytotec®) Versus Orally Misoprostol as a Tablet (Angusta®) for Induction of Labor
- First Posted Date
- 2022-06-21
- Last Posted Date
- 2023-08-18
- Lead Sponsor
- Karolinska Institutet
- Target Recruit Count
- 884
- Registration Number
- NCT05424445
- Locations
- 🇸🇪
Södersjukhuset, Stockholm, Sweden
Atorvastatin as a Potential Adjunct to Misoprostol for Termination of Pregnancy
- Conditions
- Interventions
- First Posted Date
- 2022-04-25
- Last Posted Date
- 2024-02-01
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 9
- Registration Number
- NCT05342974
- Locations
- 🇺🇸
Planned Parenthood Association of Utah, Salt Lake City, Utah, United States
Blood Loss During Cesarean Delivery in Placenta Previa Patients
- Conditions
- Interventions
- First Posted Date
- 2022-04-22
- Last Posted Date
- 2023-01-06
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 81
- Registration Number
- NCT05340205
- Locations
- 🇪🇬
Kasralainy Cairo University, Giza, Egypt
Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial
- First Posted Date
- 2022-04-11
- Last Posted Date
- 2024-04-24
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 30
- Registration Number
- NCT05322252
- Locations
- 🇺🇸
Barnes-Jewish Hospital, Saint Louis, Missouri, United States
Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol
- Conditions
- Interventions
- First Posted Date
- 2022-01-31
- Last Posted Date
- 2022-06-23
- Lead Sponsor
- Ain Shams Maternity Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT05215873
- Locations
- 🇪🇬
Ain Shams Maternity Hospital, Cairo, Egypt
Mid Trimester Abortion Effectiveness by Dilapan s
- First Posted Date
- 2021-12-07
- Last Posted Date
- 2021-12-07
- Lead Sponsor
- Ain Shams Maternity Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT05147857
- Locations
- 🇪🇬
Ainshams Maternity Hospital, Cairo, Egypt
Drug Development Updates
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