Misoprostol
- Generic Name
- Misoprostol
- Brand Names
- Arthrotec, Cytotec, Mifegymiso
- Drug Type
- Small Molecule
- Chemical Formula
- C22H38O5
- CAS Number
- 59122-46-2
- Unique Ingredient Identifier
- 0E43V0BB57
- Background
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and f...
- Indication
Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients. Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers. Misoprostol is used off label for the manage...
- Associated Conditions
- Gastric Ulcer, Incomplete Abortion, Missed Abortion, Postpartum Haemorrhage (PPH)
- Associated Therapies
- Induction of cervix ripening therapy, Medically induced abortion
Uterotonics for Severe Preeclampsia
- Conditions
- Interventions
- First Posted Date
- 2021-02-16
- Last Posted Date
- 2021-02-16
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 124
- Registration Number
- NCT04756661
- Locations
- 🇪🇬
Assiut Faculty of Medicine, Assiut, Egypt
Prevention of Primary Postpartum Haemorrhage
- First Posted Date
- 2021-01-26
- Last Posted Date
- 2021-02-25
- Lead Sponsor
- Islamabad Medical and Dental College
- Target Recruit Count
- 180
- Registration Number
- NCT04724187
- Locations
- 🇵🇰
Islamabad medical and Dental College, Islamabad, Federal, Pakistan
Management of RPOC After Induced Abortion
- First Posted Date
- 2020-12-28
- Last Posted Date
- 2022-05-03
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 141
- Registration Number
- NCT04685694
- Locations
- 🇮🇱
Tel Aviv Medical Center; ,, Tel Aviv, Israel
Prostaglandins Use Before Mirena IUD Insertion in Prev CS Women During Lactational Amenorrhea
- First Posted Date
- 2020-11-27
- Last Posted Date
- 2021-01-19
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 400
- Registration Number
- NCT04646161
- Locations
- 🇪🇬
Cairo University, Cairo, Egypt
Misoprostol for Spinal Stenosis
- First Posted Date
- 2020-11-02
- Last Posted Date
- 2020-11-02
- Lead Sponsor
- Dallas VA Medical Center
- Target Recruit Count
- 23
- Registration Number
- NCT04611464
- Locations
- 🇺🇸
Dallas VA Medical Center, Dallas, Texas, United States
Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage
- First Posted Date
- 2020-10-27
- Last Posted Date
- 2022-05-24
- Lead Sponsor
- Islamabad Medical and Dental College
- Target Recruit Count
- 120
- Registration Number
- NCT04604366
- Locations
- 🇵🇰
Islamabad Medical and Dental College, Islamabad, Federal, Pakistan
Propranolol and Misoprostol Versus Misoprostol Alone for Induction of Labor in Primigravidas
- Conditions
- Interventions
- First Posted Date
- 2020-09-01
- Last Posted Date
- 2022-08-31
- Lead Sponsor
- Ahmed mohamed fathy ismail
- Target Recruit Count
- 128
- Registration Number
- NCT04533841
- Locations
- 🇪🇬
Ahmed mohamed fathy ismail, Zagazig, El Sharquia, Egypt
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
- First Posted Date
- 2020-08-17
- Last Posted Date
- 2020-08-17
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 140
- Registration Number
- NCT04514770
- Locations
- 🇪🇬
Menoufia University hospital, Shibīn Al Kawm, Menoufia, Egypt
Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device Insertion
- Conditions
- Interventions
- First Posted Date
- 2020-08-10
- Last Posted Date
- 2020-08-18
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT04505943
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women
- Conditions
- Interventions
- First Posted Date
- 2020-08-10
- Last Posted Date
- 2020-08-18
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT04505917
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Drug Development Updates
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