MedPath

Rintatolimod

Generic Name
Rintatolimod
Drug Type
Biotech
CAS Number
38640-92-5
Unique Ingredient Identifier
94325AJ25N

Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer

Early Phase 1
Completed
Conditions
Triple -Negative Breast Cancer
Estrogen Receptor Negative
Anatomic Stage IV Breast Cancer AJCC
HER2/Neu Negative
Progesterone Receptor Negative
Interventions
Procedure: Biopsy
Procedure: Chemokine Modulation Therapy
Biological: Recombinant Interferon Alfa-2b
Biological: Pembrolizumab
First Posted Date
2018-07-26
Last Posted Date
2023-07-18
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
8
Registration Number
NCT03599453
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

Phase 2
Completed
Conditions
Metastatic Carcinoma in the Liver
Recurrent Colorectal Carcinoma
Stage IV Colorectal Cancer AJCC v7
Stage IVA Colorectal Cancer AJCC v7
Stage IVB Colorectal Cancer AJCC v7
Interventions
Other: Laboratory Biomarker Analysis
Biological: Recombinant Interferon Alfa-2b
First Posted Date
2018-01-18
Last Posted Date
2022-03-02
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
19
Registration Number
NCT03403634
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

Vaccine Therapy in Combination With Rintatolimod and/or Sargramostim in Treating Patients With Stage II-IV HER2-Positive Breast Cancer

Phase 1
Completed
Conditions
Male Breast Cancer
Stage II Breast Cancer
Stage IIIA Breast Cancer
Stage IV Breast Cancer
Stage IIIB Breast Cancer
Recurrent Breast Cancer
HER2-positive Breast Cancer
Stage IIIC Breast Cancer
Interventions
Biological: HER-2/neu peptide vaccine
Biological: sargramostim
First Posted Date
2011-05-18
Last Posted Date
2020-02-10
Lead Sponsor
University of Washington
Target Recruit Count
50
Registration Number
NCT01355393
Locations
🇺🇸

Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium, Seattle, Washington, United States

The Study of the Safety and Efficacy of Ampligen in Chronic Fatigue Syndrome

Phase 3
Completed
Conditions
Chronic Fatigue Syndrome
Myalgic Encephalomyelitis
First Posted Date
2005-09-22
Last Posted Date
2013-04-17
Lead Sponsor
AIM ImmunoTech Inc.
Target Recruit Count
234
Registration Number
NCT00215800

A Phase I Clinical Trial To Evaluate the Toxicity, Antiviral and Immunomodulatory Effects of a Range of Doses of Ampligen in HIV-Infected Subjects

Phase 1
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
40
Registration Number
NCT00000713
Locations
🇺🇸

Univ of Pittsburgh Med School, Pittsburgh, Pennsylvania, United States

A Clinical Trial To Evaluate the Toxicity and Antiviral Effects of a Range of Doses of Ampligen in p24 Antigen Positive HIV-Infected Patients With AIDS or ARC

Phase 1
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
12
Registration Number
NCT00000735
Locations
🇺🇸

Milton S Hershey Med Ctr, Hershey, Pennsylvania, United States

🇺🇸

George Washington Univ Med Ctr, Washington, District of Columbia, United States

A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2012-10-19
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
20
Registration Number
NCT00001000
Locations
🇺🇸

Johns Hopkins Hosp, Baltimore, Maryland, United States

A Multicenter, Double-Blind, Controlled Study to Evaluate Ampligen

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
HEM Research
Registration Number
NCT00002269
Locations
🇺🇸

Miami Veterans Administration Med Ctr, Miami, Florida, United States

🇺🇸

Oregon Health Sciences Univ, Portland, Oregon, United States

🇺🇸

MCP Hahnemann Univ Hosp, Philadelphia, Pennsylvania, United States

and more 2 locations
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