Aripiprazole

Generic Name
Aripiprazole
Brand Names
Abilify, Aripiprazole Mylan Pharma (previously Aripiprazole Pharmathen), Abilify Maintena, Aripiprazole Accord, Aripiprazole Sandoz, Aripiprazole Zentiva
Drug Type
Small Molecule
Chemical Formula
C23H27Cl2N3O2
CAS Number
129722-12-9
Unique Ingredient Identifier
82VFR53I78
Background

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A ...

Indication

Aripiprazole is indicated for the treatment of acute manic and mixed episodes associated with bipolar I disorder, irritability associated with autism spectrum disorder, schizophrenia, and Tourette's disorder. It is also used as an adjunctive treatment of major depressive disorder.[L45859 An injectable formulation of aripiprazole is indicated for agitation as...

Associated Conditions
Agitation, Bipolar 1 Disorder, Irritability, Major Depressive Disorder (MDD), Mixed manic depressive episode, Psychosis, Psychotic Depression, Schizophrenia, Tourette's Disorder (TD), Acute Manic episode
Associated Therapies
Monotherapy

A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults

First Posted Date
2013-09-13
Last Posted Date
2019-04-18
Lead Sponsor
New York State Psychiatric Institute
Registration Number
NCT01942187
Locations
🇺🇸

New York State Psychiatric Institute, New York, New York, United States

A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Schizophrenia

Phase 3
Completed
Conditions
Interventions
First Posted Date
2013-09-13
Last Posted Date
2017-06-28
Lead Sponsor
Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
68
Registration Number
NCT01942148

Antipsychotic Effects on Brain Function in Schizophrenia

First Posted Date
2013-08-01
Last Posted Date
2020-04-20
Lead Sponsor
University of California, San Francisco
Target Recruit Count
4
Registration Number
NCT01913327
Locations
🇺🇸

University of California, San Francisco, California, United States

A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis

First Posted Date
2013-03-19
Last Posted Date
2015-02-04
Lead Sponsor
Wei Hao
Target Recruit Count
50
Registration Number
NCT01813643
Locations
🇨🇳

The Second Xiangya Hospital of Central University, Changsha, Hunan, China

An Study of Aripiprazole in the Treatment of Methamphetamine Dependence

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2013-03-19
Last Posted Date
2015-02-04
Lead Sponsor
Wei Hao
Target Recruit Count
10
Registration Number
NCT01813656
Locations
🇨🇳

The Second Xiangya Hospital of Central University, Changsha, Hunan, China

A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum Disorders

First Posted Date
2012-12-05
Last Posted Date
2013-03-14
Lead Sponsor
Si Tianmei
Target Recruit Count
120
Registration Number
NCT01742390
Locations
🇨🇳

The first hospital of Hebei Province University, Shijiazhuang, Hebei, China

🇨🇳

Institute of mental health, Peking University, Beijing, Beijing, China

Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI

First Posted Date
2012-12-03
Last Posted Date
2016-05-25
Lead Sponsor
University of British Columbia
Target Recruit Count
83
Registration Number
NCT01739127
Locations
🇨🇦

BC Mental Health & Addictions Research Institute, Vancouver, British Columbia, Canada

Safety and Tolerability of Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-11-16
Last Posted Date
2015-10-16
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
110
Registration Number
NCT01727713
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