Epinephrine
- Generic Name
- Epinephrine
- Brand Names
- Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13NO3
- CAS Number
- 51-43-4
- Unique Ingredient Identifier
- YKH834O4BH
- Background
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...
- Indication
Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...
- Associated Conditions
- Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
- Associated Therapies
- -
Control of Iatrogenic Endobronchial Bleeding by Tranexamic Acid, Adrenalin and Hemagglutinase
- Conditions
- Interventions
- First Posted Date
- 2023-11-28
- Last Posted Date
- 2023-11-28
- Lead Sponsor
- China-Japan Friendship Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT06149091
- Locations
- 🇨🇳
China-Japan Friendship Hospital, BeiJing, Beijing, China
Prophylactic Tranexamic Acid Versus Adrenaline During Flexible Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2023-11-24
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Clinical Hospital Centre Zagreb
- Target Recruit Count
- 840
- Registration Number
- NCT06145191
- Locations
- 🇭🇷
University Hospital Centre Zagreb, Zagreb, Croatia
Epinephrine to Prevent Postintubation Collapse in Shocked ICU Patients
- First Posted Date
- 2023-11-03
- Last Posted Date
- 2023-11-08
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 44
- Registration Number
- NCT06115473
- Locations
- 🇪🇬
Ain Shams University Hospitals at Intensive care units department, Cairo, Egypt
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
- Conditions
- Interventions
- First Posted Date
- 2023-11-01
- Last Posted Date
- 2024-05-02
- Lead Sponsor
- Damascus University
- Target Recruit Count
- 80
- Registration Number
- NCT06112548
- Locations
- 🇸🇾
Damascus university, Damascus, Syrian Arab Republic
Study of Inhaled DMC-IH1 and Intramuscular (EpiPen®) Epinephrine in Healthy Male and Female Participants.
- First Posted Date
- 2023-08-28
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- De Motu Cordis
- Target Recruit Count
- 24
- Registration Number
- NCT06013150
- Locations
- 🇦🇺
CMAX Clinical Research, Adelaide, South Australia, Australia
Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-08-16
- Last Posted Date
- 2023-12-19
- Lead Sponsor
- Hartford Hospital
- Target Recruit Count
- 38
- Registration Number
- NCT05996133
- Locations
- 🇺🇸
Hartford Hospital, Hartford, Connecticut, United States
Role of Adrenaline in in the Inflammatory Response in Diabetes
- Conditions
- Interventions
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2024-11-21
- Lead Sponsor
- Cees Tack
- Target Recruit Count
- 30
- Registration Number
- NCT05990933
- Locations
- 🇳🇱
Radboud UMC, Nijmegen, Gelderland, Netherlands
The Use of Lidocaine Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision
- Conditions
- Interventions
- First Posted Date
- 2023-08-07
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- Vrije Universiteit Brussel
- Target Recruit Count
- 50
- Registration Number
- NCT05978687
- Locations
- 🇧🇪
UZ Brussel, Brussel, Brussels, Belgium
The PAIN (Pelvic Area Injection for Numbness) Study
- Conditions
- Interventions
- First Posted Date
- 2023-08-02
- Last Posted Date
- 2024-12-09
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT05972681
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension After Spinal Anesthesia for Cesarean Delivery
- Conditions
- Interventions
- First Posted Date
- 2023-05-31
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 196
- Registration Number
- NCT05881915
- Locations
- 🇪🇬
Yasmin Ibrahim, Cairo, Egypt
Drug Development Updates
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