Nebivolol
- Generic Name
- Nebivolol
- Brand Names
- Bystolic
- Drug Type
- Small Molecule
- Chemical Formula
- C22H25F2NO4
- CAS Number
- 118457-14-0
- Unique Ingredient Identifier
- 030Y90569U
- Background
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta blockers are generally not first l...
- Indication
Nebivolol is indicated to treat hypertension.
- Associated Conditions
- Hypertension
- Associated Therapies
- -
Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive Patients
- First Posted Date
- 2008-08-14
- Last Posted Date
- 2011-04-26
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 491
- Registration Number
- NCT00734630
- Locations
- 🇺🇸
Forest Investigative Site 024, Anaheim, California, United States
🇺🇸Forest Investigative Site 025, Chicago, Illinois, United States
🇺🇸Forest Investigative Site 057, Chicago, Illinois, United States
Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients
- Conditions
- Interventions
- First Posted Date
- 2008-05-23
- Last Posted Date
- 2011-07-22
- Lead Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
- Target Recruit Count
- 291
- Registration Number
- NCT00683124
- Locations
- 🇮🇹
IRCCS Foundation San Matteo Hospital, Pavia, Italy
The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease
- Conditions
- Interventions
- First Posted Date
- 2008-05-07
- Last Posted Date
- 2010-09-28
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 39
- Registration Number
- NCT00673075
- Locations
- 🇺🇸
Forest Investigative Site, Carrollton, Texas, United States
🇺🇸Forest Investigator Site, Florence, South Carolina, United States
A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive Patients
- First Posted Date
- 2008-04-01
- Last Posted Date
- 2010-09-20
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 12
- Registration Number
- NCT00648895
- Locations
- 🇺🇸
Forest Investigative Site, Houston, Texas, United States
Study to Evaluate Symptoms in Patients Treated With Nebivolol or Metoprolol Extended-release (ER) for Hypertension
- First Posted Date
- 2007-10-22
- Last Posted Date
- 2019-05-21
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 49
- Registration Number
- NCT00547300
- Locations
- 🇺🇸
Forest Research Institute 033, Westlake Village, California, United States
🇺🇸Forest Research Institute 025, Roseville, California, United States
🇺🇸Forest Research Institute 028, Beverly Hills, California, United States
Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2007-08-17
- Last Posted Date
- 2010-09-16
- Lead Sponsor
- Centro Cardiologico Monzino
- Target Recruit Count
- 60
- Registration Number
- NCT00517725
- Locations
- 🇮🇹
Centro Cardiologico Monzino, University of Milan, Milan, Italy
A Study of the Safety and Efficacy of Long-Term Nebivolol Use in Hypertensive Patients
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2005-12-16
- Lead Sponsor
- Mylan Bertek Pharmaceuticals
- Target Recruit Count
- 845
- Registration Number
- NCT00200499
- Locations
- 🇺🇸
Mylan Pharmaceuticals Inc., Morgantown, West Virginia, United States
A Study Evaluating the Effects of Nebivolol on Blood Pressure in Hypertensive Patients
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2005-09-20
- Lead Sponsor
- Mylan Bertek Pharmaceuticals
- Target Recruit Count
- 825
- Registration Number
- NCT00200460
- Locations
- 🇺🇸
Mylan Pharmaceuticals Inc., Morgantown, West Virginia, United States
A Study of the Safety and Efficacy of Nebivolol in Hypertensive Patients
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2005-09-20
- Lead Sponsor
- Mylan Bertek Pharmaceuticals
- Target Recruit Count
- 800
- Registration Number
- NCT00200473
- Locations
- 🇺🇸
Mylan Pharmaceuticals Inc., Morgantown, West Virginia, United States
A Study of the Efficacy and Safety of Nebivolol Added to Existing Antihypertensive Treatment in Patients With Hypertension
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2005-09-20
- Lead Sponsor
- Mylan Bertek Pharmaceuticals
- Target Recruit Count
- 600
- Registration Number
- NCT00200434
- Locations
- 🇺🇸
Mylan Pharmaceuticals Inc., Morgantown, West Virginia, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.