Nebivolol

Generic Name
Nebivolol
Brand Names
Bystolic
Drug Type
Small Molecule
Chemical Formula
C22H25F2NO4
CAS Number
118457-14-0
Unique Ingredient Identifier
030Y90569U
Background

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta blockers are generally not first l...

Indication

Nebivolol is indicated to treat hypertension.

Associated Conditions
Hypertension
Associated Therapies
-

A Safety Evaluation of ECG Intervals and Blood Pressure in Normal Healthy Volunteers After Use of Nebivolol, Atenolol, Moxifloxacin, or Placebo

Phase 1
Completed
Conditions
First Posted Date
2005-09-12
Last Posted Date
2005-09-12
Lead Sponsor
Mylan Bertek Pharmaceuticals
Target Recruit Count
260
Registration Number
NCT00158093
Locations
🇺🇸

SFBC International, Inc., Miami, Florida, United States

Dosing Study of the Effects of Nebivolol on Blood Pressure in Black Patients With Mild to Moderate Hypertension

Phase 3
Completed
Conditions
First Posted Date
2005-09-05
Last Posted Date
2005-09-14
Lead Sponsor
Mylan Bertek Pharmaceuticals
Target Recruit Count
300
Registration Number
NCT00145236
Locations
🇺🇸

Mylan Pharmaceuticals Inc., Morgantown, West Virginia, United States

The Effect of Nebivolol on Insulin Sensitivity

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2005-08-02
Last Posted Date
2019-12-12
Lead Sponsor
Imperial College London
Target Recruit Count
54
Registration Number
NCT00125853
Locations
🇬🇧

Imperial College London, Paddington, London, United Kingdom

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