Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
Treatment Resistant Depression (Pilot)
- Conditions
- Interventions
- First Posted Date
- 2010-08-10
- Last Posted Date
- 2023-09-15
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 20
- Registration Number
- NCT01179009
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
Clonidine for Neonatal Abstinence Syndrome Study
- Conditions
- Interventions
- First Posted Date
- 2010-08-05
- Last Posted Date
- 2014-01-06
- Lead Sponsor
- Baystate Medical Center
- Target Recruit Count
- 68
- Registration Number
- NCT01175668
- Locations
- 🇺🇸
NICU @ Baystate Children's Hospital, Springfield, Massachusetts, United States
Use of Transdermal Clonidine in Trauma Patients
- First Posted Date
- 2010-06-09
- Last Posted Date
- 2017-06-14
- Lead Sponsor
- Memorial Health University Medical Center
- Target Recruit Count
- 22
- Registration Number
- NCT01139996
- Locations
- 🇺🇸
Memorial Health University Medical Center, Savannah, Georgia, United States
Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)
- Conditions
- Interventions
- First Posted Date
- 2010-06-03
- Last Posted Date
- 2013-01-25
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 16
- Registration Number
- NCT01136278
- Locations
- 🇨🇭
Clinical Pharmacology & Toxicology, University Hospital Basel, Basel, Switzerland
Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery
- Conditions
- Interventions
- First Posted Date
- 2010-04-29
- Last Posted Date
- 2015-09-14
- Lead Sponsor
- Cedars-Sinai Medical Center
- Registration Number
- NCT01112878
- Locations
- 🇺🇸
Cedars Sinai Medical Center, Los Angeles, California, United States
Neonatal Spinal Anesthesia: Effects of the Addition of Clonidine
- First Posted Date
- 2010-02-25
- Last Posted Date
- 2010-02-25
- Lead Sponsor
- University Hospital, Montpellier
- Target Recruit Count
- 120
- Registration Number
- NCT01075490
- Locations
- 🇫🇷
CHU de Montpellier, Montpellier, France
Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)
- Conditions
- Interventions
- First Posted Date
- 2010-01-05
- Last Posted Date
- 2013-11-08
- Lead Sponsor
- Towson Orthopaedic Associates
- Target Recruit Count
- 160
- Registration Number
- NCT01042093
The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial
- Conditions
- Interventions
- First Posted Date
- 2009-12-29
- Last Posted Date
- 2012-11-20
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT01040429
- Locations
- 🇳🇴
Dept. of Pediatrics, Oslo University Hospital Rikshospitalet, Oslo, Norway
Transversus Abdominis Plane (TAP) Block for Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2009-11-18
- Last Posted Date
- 2017-10-23
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 90
- Registration Number
- NCT01015807
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
🇧🇷Hospital e Maternidade Santa Joana, São Paulo, Brazil
Systematic Clonidine for Epidural Analgesia in Labour
- First Posted Date
- 2009-09-23
- Last Posted Date
- 2013-04-04
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Target Recruit Count
- 124
- Registration Number
- NCT00983125
- Locations
- 🇫🇷
CHU Clermont-Ferrand, Clermont-Ferrand, France
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.