Lipoic acid

Generic Name
Lipoic acid
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C8H14O2S2
CAS Number
1200-22-2
Unique Ingredient Identifier
VLL71EBS9Z
Background

A vitamin-like antioxidant.

Indication

For nutritional supplementation, also for treating dietary shortage or imbalance.

Associated Conditions
Diabetic Neuropathies, Type 2 Diabetes Mellitus
Associated Therapies
Dietary and Nutritional Therapies, Nutritional supplementation

Alpha-lipoic Acid Reduces Left Ventricular Mass in Normotensive Type 2 Diabetic Patients With Coronary Artery Disease

First Posted Date
2013-06-13
Last Posted Date
2015-08-21
Lead Sponsor
Wuhan General Hospital of Guangzhou Military Command
Target Recruit Count
66
Registration Number
NCT01877590
Locations
🇨🇳

Wuhan General Hospital, Wuhan, Hubei, China

Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy

First Posted Date
2012-02-02
Last Posted Date
2016-01-27
Lead Sponsor
University of Campania "Luigi Vanvitelli"
Target Recruit Count
90
Registration Number
NCT01524861
Locations
🇮🇹

Dept Geriatric and Metabolic diseases SUN, Naples, Italy

A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants

First Posted Date
2011-12-19
Last Posted Date
2019-03-11
Lead Sponsor
Pujol, Aurora, M.D.
Target Recruit Count
13
Registration Number
NCT01495260
Locations
🇪🇸

Hospital Universitari de Bellvitge, L'Hospitalet de LLobregat, Barcelona, Spain

Effects of Rosiglitazone and Alpha-lipoic Acid on the Patients With Pathologically Proved NASH

First Posted Date
2011-08-01
Last Posted Date
2011-08-19
Lead Sponsor
Seoul St. Mary's Hospital
Target Recruit Count
26
Registration Number
NCT01406704

Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Neuropathy

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-03-11
Last Posted Date
2014-10-02
Lead Sponsor
Northwestern University
Target Recruit Count
9
Registration Number
NCT01313117
Locations
🇺🇸

Northwestern Medical Faculty Foundation, Chicago, Illinois, United States

Lipoic Acid as a Treatment for Acute Optic Neuritis

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-02-11
Last Posted Date
2019-04-26
Lead Sponsor
Oregon Health and Science University
Target Recruit Count
31
Registration Number
NCT01294176
Locations
🇺🇸

Oregon Health & Science University, Portland, Oregon, United States

Efficacy and Safety Study of Thioctacid Oral Tablets 600mg to Treat Chinese Diabetic Patients With Distal Symmetric Polyneuropathy

Phase 2
Conditions
Interventions
First Posted Date
2010-10-20
Last Posted Date
2010-10-21
Lead Sponsor
NovaMed Pharmaceuticals Inc.
Target Recruit Count
200
Registration Number
NCT01224353
Locations
🇨🇳

The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

🇨🇳

Wuxi No.2 People's Hospital, Wuxi, Jiangsu, China

🇨🇳

Jiangsu Provincial People's Hospital, Nanjing, Jiangsu, China

and more 2 locations

Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)

First Posted Date
2010-08-26
Last Posted Date
2017-02-02
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
54
Registration Number
NCT01188811
Locations
🇺🇸

VA Portland Health Care System, Portland, OR, Portland, Oregon, United States

The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-01-26
Last Posted Date
2012-10-02
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
15
Registration Number
NCT01056497
Locations
🇨🇦

Toronto General Hospital, Toronto, Ontario, Canada

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