Tamsulosin
- Generic Name
- Tamsulosin
- Brand Names
- Flomax, Jalyn
- Drug Type
- Small Molecule
- Chemical Formula
- C20H28N2O5S
- CAS Number
- 106133-20-4
- Unique Ingredient Identifier
- G3P28OML5I
- Background
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor mus...
- Indication
Tamsulosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia.
Tamsulosin is also used off label for the treatment of ureteral stones, prostatitis, and female voiding dysfunction.
- Associated Conditions
- Benign Prostatic Hyperplasia (BPH), Benign Prostatic Hypertrophy, Bladder Outlet Obstruction, Ureteral Calculus
- Associated Therapies
- -
Efficacy of Silodosin in the Treatment of Symptomatic Benign Prostatic Hyperplasia (BPH)
- First Posted Date
- 2019-09-27
- Last Posted Date
- 2019-09-27
- Target Recruit Count
- 141
- Registration Number
- NCT04107896
- Locations
- 🇧🇩
Maidul islam, Dhaka, Bangladesh
Prophylactic Administration of Alpha Blockers for Prevention of Urinary Retention in Males Undergoing Inguinal Hernia Repair Under Spinal Anaesthesia.
- Conditions
- Interventions
- First Posted Date
- 2019-06-06
- Last Posted Date
- 2021-11-26
- Lead Sponsor
- Georgios Koukoulis
- Target Recruit Count
- 100
- Registration Number
- NCT03976934
- Locations
- 🇬🇷
General Hospital Of Larissa, Larissa, Greece
🇬🇷University General Hospital of Larissa, Larissa, Greece
Effect of Tamsulosin on PE Compared With Paroxetine Hydrochloride
- Conditions
- Interventions
- First Posted Date
- 2019-03-19
- Last Posted Date
- 2019-03-19
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 160
- Registration Number
- NCT03879746
Prevention of Postoperative Urinary Retention with Treatment of Tamsulosin 5 Days Prior to Lower Limb Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2019-01-17
- Last Posted Date
- 2024-10-24
- Lead Sponsor
- Kantonsspital Graubünden
- Target Recruit Count
- 170
- Registration Number
- NCT03808155
- Locations
- 🇨🇭
Kantonsspital Graubünden, Chur, Graubünden, Switzerland
Use of Hyoscyamine Versus Tamsulosin for Management of Ureteral Stent Irritation
- Conditions
- Interventions
- First Posted Date
- 2018-11-23
- Last Posted Date
- 2024-12-03
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 5
- Registration Number
- NCT03750656
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:
- Conditions
- Interventions
- First Posted Date
- 2018-10-17
- Last Posted Date
- 2023-10-12
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 200
- Registration Number
- NCT03709992
- Locations
- 🇪🇬
Ahmed R EL-Nahas, Mansoura, Kuwait, Egypt
Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-05-14
- Last Posted Date
- 2021-11-08
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 132
- Registration Number
- NCT03524339
- Locations
- 🇺🇸
University Hospitals, Cleveland, Ohio, United States
🇺🇸University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
Prophylactic Alpha-blockers in the Prevention of Urinary Retention Post Inguinal Hernia Repair
- Conditions
- Interventions
- First Posted Date
- 2017-10-19
- Last Posted Date
- 2017-10-19
- Lead Sponsor
- National University Hospital, Singapore
- Target Recruit Count
- 300
- Registration Number
- NCT03314259
Hernia Surgery Urinary Retention
- First Posted Date
- 2017-01-20
- Last Posted Date
- 2018-03-23
- Lead Sponsor
- Memorial Health University Medical Center
- Target Recruit Count
- 140
- Registration Number
- NCT03027115
- Locations
- 🇺🇸
Memorial Health University Medical Center, Savannah, Georgia, United States
Preoperative Administration of Tamsulosin for Prevention of Post Operative Urinary Retention in Males Undergoing Elective Inguinal Hernia Repair
- Conditions
- Interventions
- First Posted Date
- 2016-11-08
- Last Posted Date
- 2019-07-30
- Lead Sponsor
- Ascension Health
- Target Recruit Count
- 210
- Registration Number
- NCT02958878
Drug Development Updates
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