Acetylcysteine
- Generic Name
- Acetylcysteine
- Brand Names
- Acetadote
- Drug Type
- Small Molecule
- Chemical Formula
- C5H9NO3S
- CAS Number
- 616-91-1
- Unique Ingredient Identifier
- WYQ7N0BPYC
- Background
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose. Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.
Acetylcysteine was granted FDA approval on 14 September 1963.
- Indication
Acetylcysteine is indicated for mucolytic therapy and in the management of acetaminophen overdose.
- Associated Conditions
- Acetaminophen Overdose, Chronic Rhinitis, Corneal Diseases, Corneal ulceration, Crusting Rhinitis, Keratopathy, Rhinitis, Sinusitis, Vasomotor Rhinitis, Acute Rhinitis, Subacute Rhinitis
- Associated Therapies
- Airway secretion clearance therapy
Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit
Not Applicable
Completed
- Conditions
- First Posted Date
- 2005-08-18
- Last Posted Date
- 2009-06-23
- Target Recruit Count
- 260
- Registration Number
- NCT00131521
- Locations
- 🇺🇸
Univesity Hospital, San Antonio, Texas, United States
An Investigation of N-acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Phase 2
Completed
- Conditions
- Interventions
- First Posted Date
- 2005-07-21
- Last Posted Date
- 2014-11-07
- Lead Sponsor
- Linda F. Barr, M.D.
- Target Recruit Count
- 80
- Registration Number
- NCT00122018
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma
Phase 2
Completed
- Conditions
- First Posted Date
- 2003-04-25
- Last Posted Date
- 2013-06-25
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 80
- Registration Number
- NCT00003346
- Locations
- 🇺🇸
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
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