Methylphenidate
- Generic Name
- Methylphenidate
- Brand Names
- Adhansia, Aptensio, Biphentin, Concerta, Cotempla, Daytrana, Foquest, Jornay, Metadate, Methylin, Quillichew, Quillivant, Relexxii, Ritalin
- Drug Type
- Small Molecule
- Chemical Formula
- C14H19NO2
- CAS Number
- 113-45-1
- Unique Ingredient Identifier
- 207ZZ9QZ49
- Background
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve ...
- Indication
Methylphenidate is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy.
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Narcolepsy
- Associated Therapies
- -
Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
- Conditions
- Interventions
- First Posted Date
- 2014-06-03
- Last Posted Date
- 2023-04-11
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 142
- Registration Number
- NCT02153944
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO PET
- Conditions
- Interventions
- First Posted Date
- 2014-06-02
- Last Posted Date
- 2023-02-16
- Lead Sponsor
- Yale University
- Target Recruit Count
- 1
- Registration Number
- NCT02152670
- Locations
- 🇺🇸
Connecticut Mental Health Center, New Haven, Connecticut, United States
Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
- First Posted Date
- 2014-05-28
- Last Posted Date
- 2018-10-04
- Target Recruit Count
- 11
- Registration Number
- NCT02148783
- Locations
- 🇺🇸
National Institutes of Health, Clinical Center., Bethesda, Maryland, United States
Impact of CES1 Genotype on Metabolism of Methylphenidate
- Conditions
- Interventions
- First Posted Date
- 2014-05-26
- Last Posted Date
- 2014-10-13
- Lead Sponsor
- Bispebjerg Hospital
- Target Recruit Count
- 78
- Registration Number
- NCT02147535
- Locations
- 🇩🇰
Department of Clinical Pharmacology, Bispebjerg University Hospital, Copenhagen, Denmark
Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype
- Conditions
- Interventions
- First Posted Date
- 2014-05-09
- Last Posted Date
- 2014-07-30
- Lead Sponsor
- Bispebjerg Hospital
- Target Recruit Count
- 44
- Registration Number
- NCT02135263
- Locations
- 🇩🇰
Department of Clinical Pharmacology, Bispebjerg University Hospital, Copenhagen, Denmark
Symptomatic Treatment of Vascular Cognitive Impairment
- First Posted Date
- 2014-03-28
- Last Posted Date
- 2016-05-02
- Lead Sponsor
- Amsterdam UMC, location VUmc
- Target Recruit Count
- 30
- Registration Number
- NCT02098824
- Locations
- 🇳🇱
VU University Medical Center, Amsterdam, Netherlands
Methylphenidate vs. Risperidone for the Treatment of Children and Adolescents With ADHD and Disruptive Disorders
- Conditions
- Interventions
- First Posted Date
- 2014-02-17
- Last Posted Date
- 2020-03-18
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 5
- Registration Number
- NCT02063945
- Locations
- 🇮🇱
Sheba medical center, Tel Hashomer, Israel
Reversal of General Anesthesia With Methylphenidate
- Conditions
- Interventions
- First Posted Date
- 2014-01-31
- Last Posted Date
- 2019-08-22
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 32
- Registration Number
- NCT02051452
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Examining Tolerance to CNS Stimulants in ADHD
- Conditions
- Interventions
- First Posted Date
- 2014-01-20
- Last Posted Date
- 2020-06-09
- Lead Sponsor
- Florida International University
- Target Recruit Count
- 267
- Registration Number
- NCT02039908
- Locations
- 🇺🇸
Florida International University Center for Children and Families, Miami, Florida, United States
Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
- First Posted Date
- 2013-12-27
- Last Posted Date
- 2020-02-28
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 24
- Registration Number
- NCT02021214
- Locations
- 🇺🇸
UCSD Psychiatry Clinical Research, San Diego, California, United States
Drug Development Updates
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