Methylphenidate

Generic Name
Methylphenidate
Brand Names
Adhansia, Aptensio, Biphentin, Concerta, Cotempla, Daytrana, Foquest, Jornay, Metadate, Methylin, Quillichew, Quillivant, Relexxii, Ritalin
Drug Type
Small Molecule
Chemical Formula
C14H19NO2
CAS Number
113-45-1
Unique Ingredient Identifier
207ZZ9QZ49
Background

Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve ...

Indication

Methylphenidate is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy.

Associated Conditions
Attention Deficit Hyperactivity Disorder (ADHD), Narcolepsy
Associated Therapies
-

Large-scale Brain Organization During Cognitive Control in ADHD

First Posted Date
2020-04-16
Last Posted Date
2021-01-12
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
37
Registration Number
NCT04349917
Locations
🇺🇸

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

The Effects of a Single Dose of Methylphenidate on Motor Performance

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2020-02-25
Last Posted Date
2023-12-20
Lead Sponsor
Loewenstein Hospital
Target Recruit Count
200
Registration Number
NCT04283604
Locations
🇮🇱

Sharon Tsuk, Netanya, Israel

The Role of Methylphenidate on Performance in the Cold

First Posted Date
2020-02-25
Last Posted Date
2021-02-09
Lead Sponsor
Brock University
Target Recruit Count
24
Registration Number
NCT04283877
Locations
🇨🇦

Environmental Ergonomic Laboratory - Brock University, St. Catharines, Ontario, Canada

Differences by Sex and Genotype in the Effects of Stress on Executive Functions

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2020-02-18
Last Posted Date
2024-05-08
Lead Sponsor
University of British Columbia
Target Recruit Count
146
Registration Number
NCT04273880
Locations
🇨🇦

Developmental Cognitive Neuroscience Lab, Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada

Multi Neuro-functional Biomarkers for Monitoring the Effects of Treatments in ADHD Children

First Posted Date
2020-02-17
Last Posted Date
2022-08-05
Lead Sponsor
IRCCS Eugenio Medea
Target Recruit Count
20
Registration Number
NCT04272021
Locations
🇮🇹

IRCCS Eugenio Medea, Bosisio Parini, Italy

Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine]

First Posted Date
2019-11-26
Last Posted Date
2023-01-09
Lead Sponsor
Craig Rush
Target Recruit Count
8
Registration Number
NCT04178993
Locations
🇺🇸

University of Kentucky Medical Center, Lexington, Kentucky, United States

🇺🇸

University of Kentucky, Lexington, Kentucky, United States

Real World Evidence of the Efficacy and Safety of FOQUEST

First Posted Date
2019-11-05
Last Posted Date
2021-09-16
Lead Sponsor
Purdue Pharma, Canada
Target Recruit Count
257
Registration Number
NCT04152629
Locations
🇨🇦

Health Sciences North, Sudbury, Ontario, Canada

🇨🇦

Matheson Centre for Mental Health Research & Education, University of Calgary, Calgary, Alberta, Canada

🇨🇦

Alpha recherche clinique, Québec, Quebec, Canada

and more 8 locations

A Study on Suicidality, Psychosis or Substance Abuse With Methylphenidate, Atomoxetine, Amphetamine/Dextroamphetamine or Lisdexamfetamine

First Posted Date
2019-10-21
Last Posted Date
2019-11-08
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
430000
Registration Number
NCT04132557
Locations
🇺🇸

Janssen Investigative Site, Titusville, New Jersey, United States

The Neuroprotective Effects of Methylphenidate and Atomoxetine in Children With ADHD: A Lipidomic Study

First Posted Date
2019-05-03
Last Posted Date
2024-04-16
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
105
Registration Number
NCT03936491
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of Consciousness

First Posted Date
2019-01-24
Last Posted Date
2024-04-17
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
10
Registration Number
NCT03814356
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

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