Prednisone
- Generic Name
- Prednisone
- Brand Names
- Deltasone, Rayos, Winpred
- Drug Type
- Small Molecule
- Chemical Formula
- C21H26O5
- CAS Number
- 53-03-2
- Unique Ingredient Identifier
- VB0R961HZT
- Background
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.
Prednisone was granted FDA approval on 21 February 1955.
- Indication
Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.
- Associated Conditions
- Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Combination Chemotherapy Following GM-CSF in Treating Patients With Multiple Myeloma
- Conditions
- First Posted Date
- 2004-05-21
- Last Posted Date
- 2013-12-04
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 30
- Registration Number
- NCT00003490
- Locations
- ๐บ๐ธ
Cleveland Clinic Cancer Center, Cleveland, Ohio, United States
Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia
- First Posted Date
- 2004-05-20
- Last Posted Date
- 2016-07-06
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 163
- Registration Number
- NCT00003700
- Locations
- ๐บ๐ธ
University of Illinois at Chicago Health Sciences Center, Chicago, Illinois, United States
๐บ๐ธUniversity of Chicago Cancer Research Center, Chicago, Illinois, United States
๐บ๐ธVeterans Affairs Medical Center - Chicago (Westside Hospital), Chicago, Illinois, United States
Rituximab Followed by Combination Chemotherapy in Treating Patients With Refractory or Recurrent Non-Hodgkin's Lymphoma
- Conditions
- First Posted Date
- 2004-05-04
- Last Posted Date
- 2021-10-27
- Lead Sponsor
- Medstar Health Research Institute
- Registration Number
- NCT00006669
- Locations
- ๐บ๐ธ
Washington Cancer Institute, Washington, District of Columbia, United States
๐บ๐ธFranklin Square Hospital Center, Baltimore, Maryland, United States
Rituximab in Treating Patients With Multiple Myeloma
- Conditions
- First Posted Date
- 2004-04-30
- Last Posted Date
- 2013-07-18
- Lead Sponsor
- The Cleveland Clinic
- Registration Number
- NCT00003554
- Locations
- ๐บ๐ธ
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States
Combination Chemotherapy in Treating Children With Lymphoma
- Conditions
- Interventions
- First Posted Date
- 2004-04-29
- Last Posted Date
- 2014-07-24
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 221
- Registration Number
- NCT00002590
- Locations
- ๐บ๐ธ
Children's Hospital Los Angeles, Los Angeles, California, United States
๐บ๐ธChildren's Hospital of Columbus, Columbus, Ohio, United States
๐บ๐ธChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia
- Conditions
- Interventions
- First Posted Date
- 2004-04-27
- Last Posted Date
- 2014-07-28
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 36
- Registration Number
- NCT00003783
- Locations
- ๐บ๐ธ
West Virginia University Medical School, Charleston Division, Charleston, West Virginia, United States
๐บ๐ธSimmons Cancer Center - Dallas, Dallas, Texas, United States
๐บ๐ธArizona Cancer Center, Tucson, Arizona, United States
Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors
- First Posted Date
- 2004-04-22
- Last Posted Date
- 2013-02-18
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 4
- Registration Number
- NCT00002463
- Locations
- ๐บ๐ธ
University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease
- Conditions
- Interventions
- First Posted Date
- 2004-04-15
- Last Posted Date
- 2014-02-26
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 99
- Registration Number
- NCT00004010
- Locations
- ๐บ๐ธ
CCOP - Merit Care Hospital, Fargo, North Dakota, United States
๐บ๐ธMayo Clinic Cancer Center, Rochester, Minnesota, United States
๐บ๐ธUniversity of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States
Octreotide With or Without Prednisone in Treating Patients With Metastatic or Recurrent Thymoma
- Conditions
- First Posted Date
- 2004-04-14
- Last Posted Date
- 2023-06-15
- Lead Sponsor
- Eastern Cooperative Oncology Group
- Target Recruit Count
- 38
- Registration Number
- NCT00003283
- Locations
- ๐บ๐ธ
CCOP - Kalamazoo, Kalamazoo, Michigan, United States
๐บ๐ธCCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States
๐บ๐ธIreland Cancer Center, Cleveland, Ohio, United States
Combination Chemotherapy in Treating Pain in Hormone Refractory Metastatic Prostate Cancer
- Conditions
- First Posted Date
- 2004-04-09
- Last Posted Date
- 2020-04-03
- Lead Sponsor
- NCIC Clinical Trials Group
- Target Recruit Count
- 227
- Registration Number
- NCT00003232
- Locations
- ๐จ๐ฆ
Cancer Care Ontario - Windsor Regional Cancer Centre, Windsor, Ontario, Canada
๐จ๐ฆCancer Care Ontario-Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
๐จ๐ฆCancer Care Ontario-London Regional Cancer Centre, London, Ontario, Canada
Drug Development Updates
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