Prednisone

Generic Name
Prednisone
Brand Names
Deltasone, Rayos, Winpred
Drug Type
Small Molecule
Chemical Formula
C21H26O5
CAS Number
53-03-2
Unique Ingredient Identifier
VB0R961HZT
Background

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.

Prednisone was granted FDA approval on 21 February 1955.

Indication

Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.

Associated Conditions
Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
Associated Therapies
Palliative Treatment

Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis

First Posted Date
2019-08-28
Last Posted Date
2023-07-28
Lead Sponsor
Indiana University
Target Recruit Count
147
Registration Number
NCT04072822
Locations
🇺🇸

University of Louisville, Louisville, Kentucky, United States

🇺🇸

Virginia Commonwealth University, Richmond, Virginia, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 5 locations

Treg Modulation With CD28 and IL-6 Receptor Antagonists

First Posted Date
2019-08-26
Last Posted Date
2024-10-09
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT04066114
Locations
🇺🇸

Cleveland Clinic Foundation: Transplantation, Cleveland, Ohio, United States

🇺🇸

University of California San Francisco School of Medicine: Transplantation, San Francisco, California, United States

🇺🇸

University of Alabama School of Medicine: Transplantation, Birmingham, Alabama, United States

and more 4 locations

A Study of Bortezomib Combined With CHEP in Peripheral T Cell Lymphoma

First Posted Date
2019-08-20
Last Posted Date
2019-08-20
Lead Sponsor
Zhejiang Cancer Hospital
Target Recruit Count
54
Registration Number
NCT04061772
Locations
🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

Study of Abiraterone Acetate in Subjects With Metastatic Castration Resistant Prostate Cancer

First Posted Date
2019-08-14
Last Posted Date
2019-08-14
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
268
Registration Number
NCT04056754
Locations
🇨🇳

TongJi medical college of HuaZhong University of Science & Technology Affiliated TongJi Hospital, Wuhan, Hubei, China

🇨🇳

Jiangsu Province Hospital, Nanjing, Jiangsu, China

🇨🇳

The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China

and more 13 locations

Weekly Steroids in Muscular Dystrophy

First Posted Date
2019-08-13
Last Posted Date
2023-09-21
Lead Sponsor
Northwestern University
Target Recruit Count
20
Registration Number
NCT04054375
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma

First Posted Date
2019-08-02
Last Posted Date
2024-07-10
Lead Sponsor
University Hospital Muenster
Target Recruit Count
683
Registration Number
NCT04043494
Locations
🇳🇱

Princess Maxima Centre for Pediatric Oncology, Utrecht, Netherlands

🇫🇷

Unité d'hématologie pédiatrique CHRU de Lille - Hôpital Jeanne de Flandre, Lille, France

🇧🇪

UZ Antwerpen Kinderhemato-oncologie, Edegem, Belgium

and more 219 locations

Biomarker Guided Treatment in DLBCL

First Posted Date
2019-07-19
Last Posted Date
2020-11-19
Lead Sponsor
Ruijin Hospital
Target Recruit Count
128
Registration Number
NCT04025593
Locations
🇨🇳

Ruijin hospital, Shanghai, Shanghai, China

Prednisone Reduction in ICU Patients With COPD Exacerbation

First Posted Date
2019-06-10
Last Posted Date
2019-06-10
Lead Sponsor
Hôpital Universitaire Fattouma Bourguiba
Target Recruit Count
192
Registration Number
NCT03981081
Locations
🇲🇦

CHU Ibn Cina, Rabat, Morocco

🇹🇳

CHU Tahar Sfar, Mahdia, Tunisia

🇲🇦

CHU Arrazi, Marrakech, Morocco

and more 1 locations
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