BAY-2927088
- Generic Name
- BAY-2927088
Expanded Access to Provide BAY2927088 for the Treatment of Locally Advanced or Metastatic NSCLC With HER2 Mutation
- Conditions
- Advanced Non-small Cell Lung CancerCancer
- First Posted Date
- 2025-01-07
- Last Posted Date
- 2025-04-29
- Lead Sponsor
- Bayer
- Registration Number
- NCT06761976
A Study to Learn More About How Well Treatment With BAY2927088 Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- First Posted Date
- 2025-01-07
- Last Posted Date
- 2025-04-30
- Lead Sponsor
- Bayer
- Target Recruit Count
- 111
- Registration Number
- NCT06760819
- Locations
- 🇨ðŸ‡
Hopitaux Universitaires de Geneve, Genève, Switzerland
🇺🇸University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸City of Hope - Duarte Cancer Center, Duarte, California, United States
A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2)
- Conditions
- Advanced Non-small Cell Lung CancerHER2 Mutation
- Interventions
- First Posted Date
- 2024-06-11
- Last Posted Date
- 2025-04-08
- Lead Sponsor
- Bayer
- Target Recruit Count
- 278
- Registration Number
- NCT06452277
- Locations
- 🇺🇸
Memorial Cancer Institute at Miramar, Miramar, Florida, United States
🇺🇸Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
🇧🇬MHAT Sveta Marina EAD, Varna, Bulgaria
A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants
- Conditions
- EGFR MutationHER2 MutationHealthy VolunteersAdvanced Non-small Cell Lung Cancer
- Interventions
- First Posted Date
- 2024-04-22
- Last Posted Date
- 2024-07-05
- Lead Sponsor
- Bayer
- Target Recruit Count
- 21
- Registration Number
- NCT06378658
- Locations
- 🇺🇸
Parexel Baltimore - Early Phase Clinical Unit, Baltimore, Maryland, United States
A Study to Learn About How BAY2927088 Affects the Level of Midazolam in the Blood When Both Drugs Are Taken Together in Healthy Participants
- Conditions
- Advanced Non-small Cell Lung CancerEGFR MutationHealthy VolunteersHER2 Mutation
- Interventions
- First Posted Date
- 2024-04-11
- Last Posted Date
- 2024-07-03
- Lead Sponsor
- Bayer
- Target Recruit Count
- 15
- Registration Number
- NCT06360211
- Locations
- 🇺🇸
Parexel Baltimore - Early Phase Clinical Unit, Baltimore, Maryland, United States
A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants
- Conditions
- Advanced Non-small Cell Lung CancerEGFR MutationHER2 MutationHealthy Volunteers
- Interventions
- First Posted Date
- 2024-04-05
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Bayer
- Target Recruit Count
- 30
- Registration Number
- NCT06348888
- Locations
- 🇺🇸
Parexel Baltimore - Early Phase Clinical Unit, Baltimore, Maryland, United States
A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants
- Conditions
- EGFR MutationHER2 MutationAdvanced Non-small Cell Lung CancerHealthy Volunteers
- Interventions
- First Posted Date
- 2024-03-26
- Last Posted Date
- 2024-07-05
- Lead Sponsor
- Bayer
- Target Recruit Count
- 15
- Registration Number
- NCT06329895
- Locations
- 🇬🇧
PAREXEL International Early Phase Clinical Unit (London), Harrow, United Kingdom
Drug Development Updates
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