Iron

Generic Name
Iron
Brand Names
Citranatal B-calm Kit, Citranatal Harmony, Concept Ob, Ferralet 90, Natafort, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
Fe
CAS Number
7439-89-6
Unique Ingredient Identifier
E1UOL152H7
Background

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-defi...

Indication

Used in preventing and treating iron-deficiency anemia.

Associated Conditions
Anemia, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Restless Legs Syndrome (RLS), Concomitant myelosuppressive chemotherapy
Associated Therapies
Nutritional supplementation, Dietary supplementation

A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2019-03-28
Last Posted Date
2024-08-12
Lead Sponsor
AMAG Pharmaceuticals, Inc.
Target Recruit Count
75
Registration Number
NCT03893045
Locations
🇺🇸

Biomedical Research LLC, Miami, Florida, United States

🇺🇸

Gwinnett Research Institute, Buford, Georgia, United States

🇵🇱

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu, Wrocław, Poland

and more 12 locations

A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)

First Posted Date
2018-08-08
Last Posted Date
2024-08-12
Lead Sponsor
AMAG Pharmaceuticals, Inc.
Target Recruit Count
129
Registration Number
NCT03619850
Locations
🇺🇸

Memorial Healthcare System, Hollywood, Florida, United States

🇺🇸

West Virginia University, Morgantown, West Virginia, United States

🇵🇱

Polish Mother's Memorial Hospital Research Institute, Łódź, Poland

and more 18 locations

Iron Isomaltoside Compared With Iron Sucrosein Peritoneal Dialysis Patients

First Posted Date
2018-08-01
Last Posted Date
2021-10-06
Lead Sponsor
The University of Hong Kong
Target Recruit Count
16
Registration Number
NCT03610230
Locations
🇭🇰

Tung Wah Hospital, Hong Kong, Hong Kong

To Assess the Impact of Ferric Carboxymaltose Compared With Iron Sucrose in Chinese Subjects on Correcting Iron Deficiency Anaemia

First Posted Date
2018-07-19
Last Posted Date
2021-06-10
Lead Sponsor
Vifor (International) Inc.
Target Recruit Count
371
Registration Number
NCT03591406
Locations
🇨🇳

The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China

Hemoglobin Optimization to Prevent Transfusion and Adverse Events in Perioperative Patients With Iron Restricted Anemia

First Posted Date
2018-05-18
Last Posted Date
2021-06-18
Lead Sponsor
Unity Health Toronto
Target Recruit Count
4
Registration Number
NCT03528564
Locations
🇨🇦

St. Michael's Hosptial, Toronto, Ontario, Canada

Iron Deficiency and FGF23 Regulation in CKD and HF

First Posted Date
2017-04-10
Last Posted Date
2019-03-20
Lead Sponsor
Northwestern University
Target Recruit Count
77
Registration Number
NCT03106298
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality

First Posted Date
2017-01-30
Last Posted Date
2024-05-13
Lead Sponsor
Universitätsklinikum Hamburg-Eppendorf
Target Recruit Count
1120
Registration Number
NCT03036462
Locations
🇩🇪

Gemeinschaftspraxis Hagenmiller/ Jeserich, Nürnberg, Germany

🇩🇪

SLK-Kliniken Heilbronn GmbH Klinikum am Plattenwald, Bad Friedrichshall, Germany

🇩🇪

Kerckhoff Klinik Bad Nauheim, Bad Nauheim, Germany

and more 54 locations

The Safety of a High-Dose, Rapid Infusion of Iron Sucrose

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2016-11-30
Last Posted Date
2017-10-18
Lead Sponsor
The Guthrie Clinic
Registration Number
NCT02977611
Locations
🇺🇸

Robert Packer Hospital, Sayre, Pennsylvania, United States

Substitution of the Normal Levels of Iron and Hemoglobin in Pregnant Women With Iron Supplement

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-11-08
Last Posted Date
2020-07-29
Lead Sponsor
Hippocration General Hospital
Target Recruit Count
50
Registration Number
NCT02957643

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

First Posted Date
2016-10-21
Last Posted Date
2020-10-06
Lead Sponsor
Pharmacosmos A/S
Target Recruit Count
1538
Registration Number
NCT02940860
Locations
🇺🇸

Pharmacosmos Investigational Site, Fairfax, Virginia, United States

🇺🇸

Pharmacosmos Investigational Site1, San Antonio, Texas, United States

🇺🇸

Pharmacosmos Investigational Site2, San Antonio, Texas, United States

and more 1 locations
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