Iron

Generic Name: Iron

Brand Names: Citranatal B-calm Kit, Citranatal Harmony, Concept Ob, Ferralet 90, Natafort, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: Fe

CAS Number: 7439-89-6

Unique Ingredient Identifier: E1UOL152H7

Background: A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-defi...

Indication: Used in preventing and treating iron-deficiency anemia.

Associated Conditions: Anemia, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Restless Legs Syndrome (RLS), Concomitant myelosuppressive chemotherapy

Associated Therapies: Nutritional supplementation, Dietary supplementation

Clinical Trials

Efficacy and Safety Study of Ulipristal Acetate in Females With Anemia Associated With Uterine Leiomyoma

Phase 3

Withdrawn

Conditions: Leiomyomas

Interventions: Drug: Ulipristal Acetate
Drug: Iron

First Posted Date: 2012-03-13

Last Posted Date: 2013-02-07

Lead Sponsor: Watson Pharmaceuticals

Registration Number: NCT01553123

Locations: 🇺🇸
Discovery Clinical Trials - Genesis Health Central Women's Care, Dallas, Texas, United States
🇺🇸
Lawrence Obstetrics-Gynecology Clinical Research, Lawrenceville, New Jersey, United States
🇺🇸
Columbus Center for Women's Health Research, Columbus, Ohio, United States

and more 43 locations

Hibiscus Sabdariffa and Centella Asiatica in the Treatment of Anemia by Iron Deficiency

Phase 3

Completed

Conditions: Iron Deficiency Anemia

Interventions: Drug: Herbal medicine
Drug: Iron

First Posted Date: 2011-08-11

Last Posted Date: 2015-02-13

Lead Sponsor: Casa Espirita Terra de Ismael

Target Recruit Count: 50

Registration Number: NCT01414374

Locations: 🇧🇷
Laboratorio M. F. Teixeira, Monte Santo de Minas, Minas Gerais, Brazil

Effects of Iron Loading and Iron Chelation Therapy on Innate Immunity During Human Endotoxemia

Not Applicable

Completed

Conditions: Anemia
Systemic Inflammatory Process

Interventions: Drug: iron sucrose
Drug: Deferasirox
Drug: endotoxin
Drug: Placebo

First Posted Date: 2011-05-06

Last Posted Date: 2015-11-17

Lead Sponsor: Radboud University Medical Center

Target Recruit Count: 30

Registration Number: NCT01349699

Trial To Evaluate the Efficacy of Intravenous Iron in Older Adults With Unexplained Anemia

Phase 2

Terminated

Conditions: Anemia
Unexplained Anemia (UAE)

Interventions: Drug: iron sucrose

First Posted Date: 2011-03-07

Last Posted Date: 2016-02-05

Lead Sponsor: Duke University

Target Recruit Count: 19

Registration Number: NCT01309659

Locations: 🇺🇸
University of Illinois, Chicago, Chicago, Illinois, United States
🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States
🇺🇸
Institute For Advanced Studies in Aging, Falls Church, Virginia, United States

and more 2 locations

Compare Efficacy/Safety of Repeat Doses of Ferumoxytol With Iron Sucrose in CKD Subjects With IDA and on Hemodialysis

Phase 4

Completed

Conditions: Chronic Kidney Disease(CKD)
Iron Deficiency Anemia Treatment

Interventions: Drug: Ferumoxytol
Drug: Iron Sucrose

First Posted Date: 2010-10-25

Last Posted Date: 2022-04-21

Lead Sponsor: AMAG Pharmaceuticals, Inc.

Target Recruit Count: 296

Registration Number: NCT01227616

Locations: 🇬🇧
For additional information regarding investigative sites for this trial , contact 1-877-411-2510 Mon-Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician, London, United Kingdom
🇨🇦
For additional information regarding investigative sites for this trial, contact 1-877-411-2510 Mon-Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) , or speak with your personal physician, Montréal, Canada
🇬🇧
For additional information regarding investigative sites for this trial, contact 1-877-411-2510 Mon-Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician, London, United Kingdom

A Randomized, Comparative, Open-label Study of IV Monofer® Administered as Maintenance Therapy by Single or Repeated Bolus Injections in Comparison With IV Iron Sucrose in Subjects With CKD-5D

Phase 3

Completed

Conditions: Chronic Kidney Disease Stage 5 (Dialysis Dependent)

Interventions: Drug: Iron sucrose
Drug: Monofer

First Posted Date: 2010-10-18

Last Posted Date: 2015-12-02

Lead Sponsor: Pharmacosmos A/S

Target Recruit Count: 351

Registration Number: NCT01222884

Locations: 🇮🇳
Jatin Kothari, Mumbai, India

IV Iron for the Anemia of Traumatic Critical Illness

Not Applicable

Completed

Conditions: Trauma
ICU Anemia

Interventions: Drug: Placebo
Drug: Iron sucrose

First Posted Date: 2010-08-12

Last Posted Date: 2018-02-05

Lead Sponsor: Denver Health and Hospital Authority

Target Recruit Count: 150

Registration Number: NCT01180894

Locations: 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
🇺🇸
NewYork Presbyterian Medical Center/Weill Cornell Medical College, New York, New York, United States
🇺🇸
University of Michigan Health Systems, Ann Arbor, Michigan, United States

and more 3 locations

Safety Assessment of Iron Sucrose (Venofer) in Patients With Chronic Kidney Disease Who Cannot Tolerate Ferumoxytol (Feraheme) or Iron Dextran (INFed or Dexferrum)

Phase 4

Withdrawn

Conditions: Iron Deficiency Anemia

First Posted Date: 2010-06-28

Last Posted Date: 2018-01-24

Lead Sponsor: American Regent, Inc.

Registration Number: NCT01151592

Locations: 🇺🇸
Luitpold Pharmaceuticals, Inc., Norristown, Pennsylvania, United States

A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia

Phase 3

Completed

Conditions: Iron Deficiency Anemia

Interventions: Drug: Iron Sucrose
Drug: Ferumoxytol

First Posted Date: 2010-05-03

Last Posted Date: 2022-04-21

Lead Sponsor: AMAG Pharmaceuticals, Inc.

Target Recruit Count: 605

Registration Number: NCT01114204

Locations: 🇬🇧
For additional information regarding investigative sites for this trial, contact 1-617-498-3300 Mon-Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., London, United Kingdom
🇱🇻
For additional this triinformation regarding investigative sites for al, contact 1-617-498-3300 Mon-Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Riga, Latvia

Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia

Phase 4

Conditions: Hip Fracture
Surgical Intervention

First Posted Date: 2010-03-10

Last Posted Date: 2010-03-10

Lead Sponsor: Hospital Clinic of Barcelona

Target Recruit Count: 360

Registration Number: NCT01084122

Locations: 🇪🇸
Servicio de Cirugía Ortopédica y Traumatología. Hospital Clinic., Barcelona, Spain

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy