Deoxycholic acid
- Generic Name
- Deoxycholic acid
- Brand Names
- Belkyra, Kybella
- Drug Type
- Small Molecule
- Chemical Formula
- C24H40O4
- CAS Number
- 83-44-3
- Unique Ingredient Identifier
- 005990WHZZ
- Background
Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness o...
- Indication
For improvement in appearance of moderate to severe fullness associated with submental fat in adults.
- Associated Conditions
- -
- Associated Therapies
- Submental fat removal therapy
Assessing the Efficacy of Repeat, Monthly Treatments of Cutaneous Neurofibromas (cNFs)
- Conditions
- Interventions
- First Posted Date
- 2024-03-08
- Last Posted Date
- 2024-03-08
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 10
- Registration Number
- NCT06300502
- Locations
- 🇺🇸
Wellman Center for Photomedicine, Boston, Massachusetts, United States
Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas
- Conditions
- Interventions
- First Posted Date
- 2023-11-15
- Last Posted Date
- 2024-02-09
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT06132165
- Locations
- 🇺🇸
Wellman Center for Photomedicine, Boston, Massachusetts, United States
Dosing and Tolerability of Deoxycholic Acid Versus Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas
- First Posted Date
- 2023-11-07
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT06120036
- Locations
- 🇺🇸
Wellman Center for Photomedicine, Boston, Massachusetts, United States
Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas
- Conditions
- Interventions
- First Posted Date
- 2021-01-29
- Last Posted Date
- 2023-11-03
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT04730583
- Locations
- 🇺🇸
Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States
Efficacy and Safety of Deoxycholic Acid Injections for Removal of Adipose Tissue in the "Bra Strap Fat" Region
- Conditions
- Interventions
- First Posted Date
- 2019-09-13
- Last Posted Date
- 2021-04-01
- Lead Sponsor
- Juva Skin & Laser Center
- Target Recruit Count
- 22
- Registration Number
- NCT04089722
- Locations
- 🇺🇸
JUVA Skin & Laser Center, New York, New York, United States
Safety and Efficacy of Deoxycholic Acid Injection for Reduction of Upper Inner Thigh Fat
- First Posted Date
- 2019-08-13
- Last Posted Date
- 2021-01-20
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 15
- Registration Number
- NCT04054011
- Locations
- 🇺🇸
University of California San Diego, San Diego, California, United States
Condition of Submental Fullness and Treatment Outcomes Registry
- First Posted Date
- 2015-05-08
- Last Posted Date
- 2018-10-05
- Lead Sponsor
- Kythera Biopharmaceuticals
- Target Recruit Count
- 1029
- Registration Number
- NCT02438813
- Locations
- 🇺🇸
Callender Center for Clinical Research, LLC, Glenn Dale, Maryland, United States
🇺🇸Maryland Laser Skin & Vein Inst, Hunt Valley, Maryland, United States
🇺🇸Facial Plastic Surgical Center, Baltimore, Maryland, United States
Safety Study of ATX-101 (Deoxycholic Acid) in Subjects With Mild or Extreme Fullness of Submental Fat
- Conditions
- Interventions
- First Posted Date
- 2014-01-14
- Last Posted Date
- 2020-02-17
- Lead Sponsor
- Kythera Biopharmaceuticals
- Target Recruit Count
- 93
- Registration Number
- NCT02035267
Drug Development Updates
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