Stannous fluoride
- Generic Name
- Stannous fluoride
- Brand Names
- Doctor's Choice, Gelato Perio Rinse, Gingi Med, Kid's Choice, PerioMed, Prodenrx Rinse
- Drug Type
- Small Molecule
- Chemical Formula
- F2Sn
- CAS Number
- 7783-47-3
- Unique Ingredient Identifier
- 3FTR44B32Q
- Background
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental lesions . It manages and prevents dental caries and gingivitis by promoting enamel mineralization , reducing gingival inflammation and bleeding through its potential broad-spectrum antibiotic effect and modulation of the microbial composition of the dental biofilm . It is an FDA-approved over-the-counter product.
- Indication
Indicated for use to relieve dental hypersensitivity, increase enamel production, prevent gingivitis and cavities, and control periodontal infections.
- Associated Conditions
- Dental Cavity
- Associated Therapies
- -
Stannous Fluoride and Gingivitis
- First Posted Date
- 2022-04-13
- Last Posted Date
- 2022-06-16
- Lead Sponsor
- Procter and Gamble
- Target Recruit Count
- 40
- Registration Number
- NCT05326373
- Locations
- 🇺🇸
Salus Research, Fort Wayne, Indiana, United States
A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride
- Conditions
- Interventions
- First Posted Date
- 2019-10-11
- Last Posted Date
- 2020-01-31
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 98
- Registration Number
- NCT04123665
- Locations
- 🇺🇸
GSK Investigational Site, Fort Wayne, Indiana, United States
Analysis of Stannous Fluoride in GCF and Subgingival Plaque
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Procter and Gamble
- Target Recruit Count
- 20
- Registration Number
- NCT03296657
- Locations
- 🇺🇸
Salus Research, Fort Wayne, Indiana, United States
The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity
- Conditions
- Interventions
- First Posted Date
- 2017-03-07
- Last Posted Date
- 2018-03-06
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 120
- Registration Number
- NCT03072719
- Locations
- 🇮🇪
GSK Investigational Site, Cork, Ireland
A Study to Evaluate Sampling Methods for Subgingival Plaque
- First Posted Date
- 2016-07-22
- Last Posted Date
- 2023-11-15
- Lead Sponsor
- Procter and Gamble
- Target Recruit Count
- 20
- Registration Number
- NCT02841839
Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
- Conditions
- Interventions
- First Posted Date
- 2016-07-14
- Last Posted Date
- 2017-05-25
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 242
- Registration Number
- NCT02832375
- Locations
- 🇺🇸
GSK Investigational Site, Las Vegas, Nevada, United States
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
- First Posted Date
- 2016-04-27
- Last Posted Date
- 2018-08-27
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 75
- Registration Number
- NCT02752958
- Locations
- 🇬🇧
GSK Investigational Site, Widnes, Cheshire, United Kingdom
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
- Conditions
- Interventions
- First Posted Date
- 2016-04-26
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 253
- Registration Number
- NCT02750943
- Locations
- 🇺🇸
GSK Investigational Site, Las Vegas, Nevada, United States
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
- Conditions
- Interventions
- First Posted Date
- 2013-04-09
- Last Posted Date
- 2015-01-26
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 119
- Registration Number
- NCT01827670
- Locations
- 🇺🇸
Salus Research, Inc., Fort Wayne, Indiana, United States
The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
- Conditions
- Interventions
- First Posted Date
- 2012-05-07
- Last Posted Date
- 2014-03-10
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 120
- Registration Number
- NCT01592864
- Locations
- 🇺🇸
BioSci Research America, Inc., Las Vegas, Nevada, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.