Stannous fluoride

Generic Name
Stannous fluoride
Brand Names
Doctor's Choice, Gelato Perio Rinse, Gingi Med, Kid's Choice, PerioMed, Prodenrx Rinse
Drug Type
Small Molecule
Chemical Formula
F2Sn
CAS Number
7783-47-3
Unique Ingredient Identifier
3FTR44B32Q
Background

Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental lesions . It manages and prevents dental caries and gingivitis by promoting enamel mineralization , reducing gingival inflammation and bleeding through its potential broad-spectrum antibiotic effect and modulation of the microbial composition of the dental biofilm . It is an FDA-approved over-the-counter product.

Indication

Indicated for use to relieve dental hypersensitivity, increase enamel production, prevent gingivitis and cavities, and control periodontal infections.

Associated Conditions
Dental Cavity
Associated Therapies
-

Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity

First Posted Date
2012-05-07
Last Posted Date
2014-06-03
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
113
Registration Number
NCT01592851
Locations
🇺🇸

BioSci Research America, Inc., Las Vegas, Nevada, United States

Investigate Oral Bacteria in Adult Population

First Posted Date
2008-09-30
Last Posted Date
2011-03-23
Lead Sponsor
Colgate Palmolive
Target Recruit Count
24
Registration Number
NCT00762177
Locations
🇺🇸

Department of Oral Biology, Newark, New York, United States

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