Iberdomide

Generic Name
Iberdomide
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C25H27N3O5
CAS Number
1323403-33-3
Unique Ingredient Identifier
8V66F27X44
Background

Iberdomide (CC-220) has been used in trials studying the treatment of Systemic Lupus Erythematosus.

Associated Conditions
-
Associated Therapies
-

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma

First Posted Date
2023-06-09
Last Posted Date
2024-03-01
Lead Sponsor
Carl Ola Landgren, MD, PhD
Target Recruit Count
30
Registration Number
NCT05896228
Locations
🇺🇸

University of Miami, Miami, Florida, United States

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2023-04-24
Last Posted Date
2024-12-20
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
1216
Registration Number
NCT05827016
Locations
🇫🇷

CHU Hôpital Sud, Amiens Cedex 1, France

🇨🇳

Beijing Chaoyang Hospital, Capital Medical University, Beijing, China

🇨🇳

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China

and more 264 locations

A Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple Myeloma

First Posted Date
2022-10-18
Last Posted Date
2024-08-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
200
Registration Number
NCT05583617
Locations
🇫🇷

IGR, Villejuif, France

🇦🇺

Prince of Wales Hospital; Haematology, Randwick, New South Wales, Australia

🇦🇺

St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia

and more 11 locations

A Study of Iberdomide (CC-220) in Combination With Elotuzumab and Dexamethasone for Relapsed/Refractory Multiple Myeloma

Early Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-09-29
Last Posted Date
2024-12-02
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
7
Registration Number
NCT05560399
Locations
🇺🇸

Icahn School of Medicine, New York, New York, United States

NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide

First Posted Date
2022-09-28
Last Posted Date
2022-09-28
Lead Sponsor
PETHEMA Foundation
Target Recruit Count
480
Registration Number
NCT05558319
Locations
🇪🇸

Hospital Principe de Asturias, Alcalá de Henares, Madrid, Spain

🇪🇸

Hospital Germans Trias i Pujol (ICO BADALONA), Badalona, Spain

🇪🇸

Clinica Universidad Navarra (CUN), Pamplona, Navarra, Spain

and more 65 locations

Iberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients.

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2022-09-02
Last Posted Date
2022-09-02
Lead Sponsor
PETHEMA Foundation
Target Recruit Count
140
Registration Number
NCT05527340
Locations
🇪🇸

Hospital Universitario de Canarias, La Laguna, Spain

🇪🇸

Hospital Universitario 12 de Octubre, Madrid, Spain

🇪🇸

Clínica Universidad de Navarra, Pamplona, Spain

and more 6 locations

COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide

First Posted Date
2022-06-28
Last Posted Date
2024-03-01
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
80
Registration Number
NCT05434689
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

🇺🇸

University of Wisconsin, Madison, Wisconsin, United States

🇺🇸

Oregon Health and Science University, Portland, Oregon, United States

and more 3 locations

Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL Study

First Posted Date
2022-05-26
Last Posted Date
2023-12-22
Lead Sponsor
Mayo Clinic
Target Recruit Count
18
Registration Number
NCT05392946
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Study of Iberdomide in People With Multiple Myeloma Who Have Had an Autologous Hematopoietic Stem Cell Transplant (AHCT)

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2022-04-29
Last Posted Date
2024-10-17
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
86
Registration Number
NCT05354557
Locations
🇺🇸

Memorial Sloan Kettering Basking Ridge (Consent and Followup), Basking Ridge, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Monmouth (Consent and Follow-Up only), Middletown, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Bergen (Consent and Follow up), Montvale, New Jersey, United States

and more 5 locations

Study of Novel Regimens in Relapsed or Refractory Multiple Myeloma

First Posted Date
2022-03-21
Last Posted Date
2024-10-26
Lead Sponsor
iTeos Belgium SA
Target Recruit Count
16
Registration Number
NCT05289492
Locations
🇺🇸

Fred Hutchinson Cancer Center, Seattle, Washington, United States

🇺🇸

Eastern Connecticut Hematology & Oncology, Norwich, Connecticut, United States

🇧🇪

ZNA Cadix, Antwerp, Belgium

and more 10 locations
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