Zalutumumab

Generic Name
Zalutumumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
667901-13-5
Unique Ingredient Identifier
DA709Q5020
Background

Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.

Associated Conditions
-
Associated Therapies
-

Zalutumumab in Non-Small Cell Lung Cancer (NSCLC) Patients Refractory to Tyrosine Kinase Inhibitors

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2011-10-10
Last Posted Date
2011-10-10
Lead Sponsor
Genmab
Registration Number
NCT01449357

Zalutumumab in Combination With Radiotherapy in Head and Neck Cancer Patients Ineligible for Platinum Based Chemotherapy

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2008-07-01
Last Posted Date
2023-08-03
Lead Sponsor
Genmab
Target Recruit Count
8
Registration Number
NCT00707655
Locations
🇫🇷

Medical Oncology, Outpatient Clinic, Nantes, France

🇬🇧

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom

🇫🇷

Centre Georges-Francois Leclerc Hospital, Dijon, France

and more 5 locations

Zalutumumab With or Without Irinotecan Chemotherapy in Cetuximab-Refractory Colorectal Cancer

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2008-05-15
Last Posted Date
2023-07-18
Lead Sponsor
Genmab
Target Recruit Count
9
Registration Number
NCT00677924
Locations
🇧🇪

Hospital Erasme, Brussels, Belgium

🇧🇪

Institut Jules Bordet, Brussels, Belgium

🇧🇪

St-Luc University Hospital, Brussels, Belgium

Zalutumumab in Non-curable Patients With SCCHN

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-10-11
Last Posted Date
2023-08-03
Lead Sponsor
Genmab
Target Recruit Count
90
Registration Number
NCT00542308
Locations
🇺🇸

University Of Chicago Medical Center, Chicago, Illinois, United States

🇦🇹

Universitätsklinik für Innere Medizin III, Salzburg, Austria

🇨🇿

Nemocnice Jihlava, Jihlava, Czechia

and more 45 locations

DAHANCA 19: The Importance of the EGFr-inhibitor Zalutumumab for the Outcome After Curative Radiotherapy for HNSCC

First Posted Date
2007-07-04
Last Posted Date
2016-11-25
Lead Sponsor
Danish Head and Neck Cancer Group
Target Recruit Count
619
Registration Number
NCT00496652
Locations
🇩🇰

Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark

Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck Cancer

First Posted Date
2006-11-20
Last Posted Date
2011-12-23
Lead Sponsor
Genmab
Target Recruit Count
30
Registration Number
NCT00401401
Locations
🇳🇱

Nijmegen University Hospital, Nijmegen, Netherlands

🇸🇪

Lund University Hospital, Lund, Sweden

🇫🇷

Centre Georges-Francois Leclerc Hospital, Dijon, France

and more 4 locations

Zalutumumab in Patients With Non-curable Head and Neck Cancer

First Posted Date
2006-09-28
Last Posted Date
2013-10-15
Lead Sponsor
Genmab
Target Recruit Count
286
Registration Number
NCT00382031
Locations
🇧🇪

Cliniques Saint Pierre, Ottignies, Belgium

🇨🇦

Cross Cancer Institute, Edmonton, Alberta, Canada

🇧🇷

IBCC - Instituto Brasileiro de Combate ao Câncer, São Paulo, Brazil

and more 79 locations

Zalutumumab in Head and Neck Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2004-10-01
Last Posted Date
2023-06-28
Lead Sponsor
Genmab
Target Recruit Count
28
Registration Number
NCT00093041
Locations
🇩🇰

Rigshospitalet, Copenhagen Ø, Denmark

🇩🇰

Odense Universitetshospital, Odense, Denmark

🇩🇰

Ã…rhus Kommunehospital, Ã…rhus C, Denmark

and more 2 locations
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