Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
Steroid Resistance During COPD Exacerbations With Respiratory Failure
- First Posted Date
- 2018-09-21
- Last Posted Date
- 2020-01-18
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 46
- Registration Number
- NCT03680495
- Locations
- 🇺🇸
University of Colorado Denver, Aurora, Colorado, United States
Imatinib for Multiple Sclerosis (MS) Relapses
- First Posted Date
- 2018-09-17
- Last Posted Date
- 2021-08-02
- Lead Sponsor
- Tomas Olsson
- Target Recruit Count
- 200
- Registration Number
- NCT03674099
- Locations
- 🇳🇴
Haukeland sjukhus, Bergen, Norway
🇳🇴Akershus University Hospital, Lørenskog, Norway
🇳🇴Rikshospitalet, Oslo, Oslo, Norway
Methylprednisolone After Split-course Chemoradiotherapy For Bulky Local Advanced None-small Cell Lung Cancer
- Conditions
- Interventions
- First Posted Date
- 2018-09-07
- Last Posted Date
- 2022-11-30
- Lead Sponsor
- Sun Yat-sen University
- Target Recruit Count
- 52
- Registration Number
- NCT03661567
- Locations
- 🇨🇳
Sun yat-sen University Cancer Center, Guangzhou, Guangdong, China
Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura
- Conditions
- Interventions
- First Posted Date
- 2018-08-27
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Children's Hospital of Fudan University
- Target Recruit Count
- 150
- Registration Number
- NCT03647852
- Locations
- 🇨🇳
Shanghai Children's Medical Centre, Shanghai, China
🇨🇳Children's Hospital of Shanghai, Shanghai, China
🇨🇳Children's Hospital of Fudan University, Shanghai, China
Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2018-08-21
- Last Posted Date
- 2022-03-02
- Lead Sponsor
- Lars Wiuff Andersen
- Target Recruit Count
- 501
- Registration Number
- NCT03640949
- Locations
- 🇩🇰
Horsens Regional Hospital, Horsens, Denmark
🇩🇰Copenhagen University Hospital - Herlev, Herlev, Denmark
🇩🇰Aalborg University Hospital, Aalborg, Denmark
Scalp Infiltration With Methylprednisolone Plus Ropivacaine for Post-Craniotomy Pain in Children
- Conditions
- Interventions
- First Posted Date
- 2018-08-17
- Last Posted Date
- 2021-10-27
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT03636165
Cardiac Safe Transplants for Systemic Sclerosis
- First Posted Date
- 2018-07-20
- Last Posted Date
- 2020-08-12
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 9
- Registration Number
- NCT03593902
- Locations
- 🇺🇸
Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States
🇺🇸Northwestern University, Chicago, Illinois, United States
Impact of Intravenous Methylprednisolone Treatment on Blood Pressure
- Conditions
- Interventions
- First Posted Date
- 2018-07-18
- Last Posted Date
- 2018-07-18
- Lead Sponsor
- Medical University of Warsaw
- Target Recruit Count
- 32
- Registration Number
- NCT03590080
GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
- Conditions
- Interventions
- First Posted Date
- 2018-07-12
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Incyte Corporation
- Target Recruit Count
- 155
- Registration Number
- NCT03584516
- Locations
- 🇺🇸
Winship Cancer Institute of Emory University, Atlanta, Georgia, United States
🇺🇸Loyola University Medical Center, Maywood, Illinois, United States
🇺🇸Jefferson University Hospitals, Philadelphia, Pennsylvania, United States
Coagulation After Intravenous Methylprednisolone Administration
- Conditions
- Interventions
- First Posted Date
- 2018-05-24
- Last Posted Date
- 2018-05-24
- Lead Sponsor
- Piotr Miskiewicz
- Target Recruit Count
- 26
- Registration Number
- NCT03535090
Drug Development Updates
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