Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment

Sonographic Assessment in Severe Ulcerative Colitis Patients Admitted for Intravenous Corticosteroids and Eligible for Infliximab Rescue Therapy; a Prospective Clinician-blinded Observational Study Protocol.

First Posted Date
2019-05-08
Last Posted Date
2021-01-27
Lead Sponsor
Copenhagen University Hospital at Herlev
Target Recruit Count
50
Registration Number
NCT03942861
Locations
🇩🇰

Herlev University Hospital, Copenhagen, Herlev, Denmark

Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis

First Posted Date
2019-05-08
Last Posted Date
2023-12-14
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
100
Registration Number
NCT03942887
Locations
🇳🇱

Noordwest Ziekenhuisgroep, Alkmaar, Netherlands

🇳🇱

HagaZiekenhuis, Den Haag, Netherlands

🇳🇱

Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

and more 1 locations

Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

First Posted Date
2019-04-12
Last Posted Date
2024-08-19
Lead Sponsor
St. Jude Children's Research Hospital
Target Recruit Count
32
Registration Number
NCT03913559
Locations
🇺🇸

Rady Children's Hospital San Diego, San Diego, California, United States

🇺🇸

St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures

First Posted Date
2019-04-01
Last Posted Date
2024-05-01
Lead Sponsor
C. Liam Dwyer
Target Recruit Count
200
Registration Number
NCT03898154
Locations
🇺🇸

Geisinger Woodbine, Danville, Pennsylvania, United States

Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2019-02-25
Last Posted Date
2021-09-16
Lead Sponsor
Mayo Clinic
Target Recruit Count
44
Registration Number
NCT03852537
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Autologous Transplant To End NMO Spectrum Disorder

First Posted Date
2019-02-04
Last Posted Date
2019-11-20
Lead Sponsor
Northwestern University
Registration Number
NCT03829566
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States

Veloxis de Novo Kidney Transplant ECSWD

First Posted Date
2019-02-04
Last Posted Date
2020-05-13
Lead Sponsor
Simon Tremblay, PharmD, PhD
Target Recruit Count
60
Registration Number
NCT03828682
Locations
🇺🇸

University of Cincinnati, Cincinnati, Ohio, United States

🇺🇸

The Christ Hospital, Cincinnati, Ohio, United States

Psoriatic Oligoarthritis Intervention With Symptomatic thErapy

First Posted Date
2019-01-09
Last Posted Date
2021-05-10
Lead Sponsor
University of Oxford
Target Recruit Count
1
Registration Number
NCT03797872
Locations
🇬🇧

Oxford University Hospitals NHS Trust, Oxford, Oxfordshire, United Kingdom

Corticosteroid Treatment in the Acute Phase of Caustic Ingestion Management

First Posted Date
2018-11-30
Last Posted Date
2018-11-30
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
30
Registration Number
NCT03760354

Ruxolitinib and Steroid As First Line Therapy for Acute GVHD

First Posted Date
2018-10-10
Last Posted Date
2024-09-30
Lead Sponsor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Target Recruit Count
1
Registration Number
NCT03701698
Locations
🇨🇳

Shanghai General Hospital, Shanghai, Shanghai, China

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