Magrolimab

Generic Name
Magrolimab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
2169232-81-7
Unique Ingredient Identifier
90YIEHRFJ9
Background

Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).

Associated Conditions
-
Associated Therapies
-

Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia

First Posted Date
2021-10-15
Last Posted Date
2024-04-16
Lead Sponsor
Gilead Sciences
Target Recruit Count
378
Registration Number
NCT05079230
Locations
🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

UC Irvine Health- Chao Family Comprehensive Cancer Center, Orange, California, United States

🇺🇸

The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

and more 161 locations

Study of Magrolimab Combination Therapy in Patients With Non-Surgically Removable Locally Advanced or Metastatic Triple-Negative Breast Cancer

First Posted Date
2021-07-12
Last Posted Date
2024-10-23
Lead Sponsor
Gilead Sciences
Target Recruit Count
92
Registration Number
NCT04958785
Locations
🇦🇺

St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia

🇺🇸

Charleston Oncology, Charleston, South Carolina, United States

🇦🇺

Peninsula Health, Frankston, Victoria, Australia

and more 39 locations

Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma

First Posted Date
2021-05-19
Last Posted Date
2024-11-01
Lead Sponsor
Gilead Sciences
Target Recruit Count
35
Registration Number
NCT04892446
Locations
🇺🇸

US Oncology, Inc., IRB, Fairfax, Virginia, United States

🇺🇸

US San Diego Moores Cancer Center, La Jolla, California, United States

🇺🇸

Stanford Cancer Institute, Palo Alto, California, United States

and more 19 locations

Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma

First Posted Date
2021-04-22
Last Posted Date
2024-10-15
Lead Sponsor
Gilead Sciences
Target Recruit Count
193
Registration Number
NCT04854499
Locations
🇺🇸

UCLA Hematology/Oncology, Los Angeles, California, United States

🇺🇸

Memorial Healthcare System, Hollywood, Florida, United States

🇧🇪

Algemeen Ziekenhuis Klina, Brasschaat, Belgium

and more 84 locations

Study of Magrolimab in Patients With Solid Tumors

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2021-04-01
Last Posted Date
2024-10-22
Lead Sponsor
Gilead Sciences
Target Recruit Count
106
Registration Number
NCT04827576
Locations
🇺🇸

Tallahassee Memorial Healthcare Cancer Center, Tallahassee, Florida, United States

🇺🇸

University of Miami, Deerfield Beach, Florida, United States

🇺🇸

Virginia Piper Cancer Center (Alliant Health), Saint Paul, Minnesota, United States

and more 45 locations

Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma

First Posted Date
2021-03-09
Last Posted Date
2024-06-21
Lead Sponsor
Stanford University
Target Recruit Count
8
Registration Number
NCT04788043
Locations
🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Stanford University, Stanford, California, United States

Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated

First Posted Date
2021-03-03
Last Posted Date
2024-04-15
Lead Sponsor
Gilead Sciences
Target Recruit Count
258
Registration Number
NCT04778397
Locations
🇦🇺

Fiona Stanley Hospital, Murdoch, Western Australia, Australia

🇦🇺

Royal Adelaide Hospital, Adelaide, South Australia, Australia

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 153 locations

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

First Posted Date
2021-03-03
Last Posted Date
2024-10-08
Lead Sponsor
Gilead Sciences
Target Recruit Count
54
Registration Number
NCT04778410
Locations
🇺🇸

Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, United States

🇺🇸

Swedish Cancer Institute, Seattle, Washington, United States

🇺🇸

USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States

and more 18 locations

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

First Posted Date
2021-02-12
Last Posted Date
2024-12-03
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
12
Registration Number
NCT04751383
Locations
🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas, United States

and more 8 locations

Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies

First Posted Date
2020-10-23
Last Posted Date
2024-07-29
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
1
Registration Number
NCT04599634
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

© Copyright 2024. All Rights Reserved by MedPath