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Antithrombin Alfa

Generic Name
Antithrombin Alfa
Brand Names
Atryn
Drug Type
Biotech
CAS Number
84720-88-7
Unique Ingredient Identifier
AWV6I5L6H2
Background

Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.

Indication

Antithrombin alfa is a recombinant antithrombin it is indicated for the prevention of peri-operative and peri-partum thromboembolic events in patients with hereditary deficiency of antithrombin.

Associated Conditions
Postoperative Thromboembolism, Postpartum thrombosis

Response of Continuous Recombinant Antithrombin Infusion in Postcardiotomy ECMO Patients

Early Phase 1
Withdrawn
Conditions
Antithrombin Deficiency Type 2
Interventions
First Posted Date
2017-03-27
Last Posted Date
2018-09-10
Lead Sponsor
Mayo Clinic
Registration Number
NCT03090893

Understanding "Heparin Resistance" in Cardiac Surgery

Phase 1
Completed
Conditions
Cardiopulmonary Bypass
Altered Heparin Response
Interventions
First Posted Date
2012-05-15
Last Posted Date
2016-12-14
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
504
Registration Number
NCT01598883
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Antithrombin III Supplementation for Cardiopulmonary Bypass in Neonates

Phase 1
Terminated
Conditions
Postoperative Hemorrhage
Interventions
First Posted Date
2010-07-08
Last Posted Date
2014-01-20
Lead Sponsor
Medical College of Wisconsin
Target Recruit Count
8
Registration Number
NCT01158729
Locations
🇺🇸

Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States

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