Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Combination Chemotherapy in Hodgkin's Disease or Non-Hodgkin's Lymphoma Not Responding to Previous Treatment

Phase 2
Completed
Conditions
First Posted Date
2003-07-30
Last Posted Date
2020-04-09
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
77
Registration Number
NCT00014209
Locations
🇨🇦

Credit Valley Hospital, Mississauga, Ontario, Canada

🇨🇦

Cancer Care Ontario-Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada

🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

and more 10 locations

Paclitaxel and Carboplatin Chemotherapy Compared With Standard Chemotherapy in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer That Cannot Be Removed During Surgery

Phase 3
Conditions
First Posted Date
2003-07-24
Last Posted Date
2013-09-20
Lead Sponsor
The Christie NHS Foundation Trust
Registration Number
NCT00004887
Locations
🇬🇧

Christie Hospital N.H.S. Trust, Manchester, England, United Kingdom

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor

First Posted Date
2003-07-09
Last Posted Date
2012-11-07
Lead Sponsor
St. Jude Children's Research Hospital
Target Recruit Count
94
Registration Number
NCT00003211
Locations
🇺🇸

Texas Children's Cancer Center, Houston, Texas, United States

🇦🇺

Royal Children's Hospital, Parkville, Victoria, Australia

🇦🇺

Children's Hospital at Westmead, Westmead, New South Wales, Australia

and more 1 locations

Combination Chemotherapy in Treating Patients With Advanced Cancer

First Posted Date
2003-06-20
Last Posted Date
2013-07-18
Lead Sponsor
Vion Pharmaceuticals
Registration Number
NCT00024323
Locations
🇺🇸

Arizona Clinical Research Center, Tucson, Arizona, United States

🇺🇸

Yale Comprehensive Cancer Center, New Haven, Connecticut, United States

Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

Phase 3
Terminated
Conditions
First Posted Date
2003-06-17
Last Posted Date
2020-12-02
Lead Sponsor
American College of Radiology Imaging Network
Registration Number
NCT00023868
Locations
🇺🇸

Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

and more 6 locations

Combination Chemotherapy in Treating Patients With Bladder Cancer

First Posted Date
2003-06-10
Last Posted Date
2016-07-14
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
42
Registration Number
NCT00014534
Locations
🇺🇸

Geisinger Medical Group, State College, Pennsylvania, United States

🇺🇸

William N. Wishard Memorial Hospital, Indianapolis, Indiana, United States

🇺🇸

Rebecca and John Moores UCSD Cancer Center, San Diego, California, United States

and more 282 locations

Combination Chemotherapy in Treating Patients With Solid Tumors

First Posted Date
2003-06-06
Last Posted Date
2013-05-15
Lead Sponsor
Ohio State University Comprehensive Cancer Center
Registration Number
NCT00009932
Locations
🇺🇸

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

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