Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Combination Chemotherapy Followed by Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-07-25
Lead Sponsor
Yale University
Target Recruit Count
10
Registration Number
NCT00003111
Locations
🇺🇸

Yale Comprehensive Cancer Center, New Haven, Connecticut, United States

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2021-02-17
Lead Sponsor
UNICANCER
Target Recruit Count
350
Registration Number
NCT00003652
Locations
🇫🇷

Centre Paul Papin, Angers, France

🇫🇷

Centre Regional Francois Baclesse, Caen, France

🇫🇷

Centre Hospitalier, Chalon Sur Saone, France

and more 45 locations

Combination Chemotherapy Regimens in Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

First Posted Date
2003-01-27
Last Posted Date
2020-04-02
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
819
Registration Number
NCT00028743
Locations
🇨🇦

Lions Gate Hospital, North Vancouver, British Columbia, Canada

🇨🇦

CancerCare Manitoba, Winnipeg, Manitoba, Canada

🇨🇦

BCCA - Cancer Centre for the Southern Interior, Kelowna, British Columbia, Canada

and more 25 locations

High-Dose Radiation Therapy Plus Chemotherapy in Treating Patients With Advanced Nose or Throat Cancer

First Posted Date
2003-01-27
Last Posted Date
2018-01-09
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
25
Registration Number
NCT00052429
Locations
🇺🇸

Memorial Sloan - Kettering Cancer Center, New York, New York, United States

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2016-02-11
Lead Sponsor
Gynecologic Oncology Group
Target Recruit Count
216
Registration Number
NCT00002546
Locations
🇺🇸

UPMC Cancer Center at Magee-Womens Hospital, Pittsburgh, Pennsylvania, United States

🇺🇸

Women's Cancer Center - Los Gatos, Los Gatos, California, United States

🇺🇸

Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center, Orange, California, United States

and more 61 locations

Radiation Therapy With or Without Epoetin Alfa in Treating Anemic Patients With Head and Neck Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2020-10-22
Lead Sponsor
Radiation Therapy Oncology Group
Registration Number
NCT00004917
Locations
🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

🇺🇸

Marlene and Stewart Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland, United States

🇺🇸

St. Agnes Cancer Center, Baltimore, Maryland, United States

and more 258 locations

Chemotherapy and Radiation Therapy in Treating Patients With Stomach Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2020-10-19
Lead Sponsor
Radiation Therapy Oncology Group
Registration Number
NCT00003862
Locations
🇺🇸

McLaren Regional Cancer Center, Flint, Michigan, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

🇺🇸

Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States

and more 52 locations

Bryostatin 1 and Cisplatin in Treating Patients With Metastatic or Unresectable Stomach Cancer

First Posted Date
2003-01-27
Last Posted Date
2014-10-01
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
12
Registration Number
NCT00006389
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

Chemotherapy Plus Surgery in Treating Patients With Stage III or Stage IV Ovarian, Peritoneal, or Fallopian Tube Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-08-05
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
704
Registration Number
NCT00003636
Locations
🇬🇧

University College of London Hospitals, London, England, United Kingdom

🇨🇦

Doctor H. Bliss Murphy Cancer Centre, St. Johns, Newfoundland and Labrador, Canada

🇦🇹

Ludwig Boltzmann Institute for Applied Cancer Research at Kaiser Franz Josef Hospital, Vienna, Austria

and more 62 locations
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