Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Combination Chemotherapy Plus Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2016-12-07
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
58
Registration Number
NCT00005601
Locations
🇺🇸

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

🇺🇸

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

🇺🇸

CCOP - Cedar Rapids Oncology Project, Cedar Rapids, Iowa, United States

and more 18 locations

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Pancreatic Cancer

First Posted Date
2003-01-27
Last Posted Date
2016-07-14
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
48
Registration Number
NCT00026403
Locations
🇺🇸

Altru Cancer Center, Grand Forks, North Dakota, United States

🇺🇸

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States

🇺🇸

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

and more 23 locations

Combination Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Stage IIIB Non-Small Cell Lung Cancer

Phase 2
Terminated
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-07-18
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
5
Registration Number
NCT00021112
Locations
🇳🇱

Academisch Ziekenhuis Utrecht, Utrecht, Netherlands

🇧🇪

Algemeen Ziekenhuis Middelheim, Antwerp, Belgium

🇳🇱

University Hospital - Rotterdam Dijkzigt, Rotterdam, Netherlands

and more 7 locations

Erlotinib and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

First Posted Date
2003-01-27
Last Posted Date
2018-10-10
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
51
Registration Number
NCT00030576
Locations
🇨🇦

Ottawa Regional Cancer Centre, Ottawa, Ontario, Canada

🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

🇨🇦

Queen's University, Kingston, Ontario, Canada

and more 3 locations

Radiation Therapy, Paclitaxel, and Cisplatin in Treating Patients With Cancer of the Cervix

First Posted Date
2003-01-27
Last Posted Date
2013-02-04
Lead Sponsor
Gynecologic Oncology Group
Target Recruit Count
29
Registration Number
NCT00003377
Locations
🇺🇸

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

🇺🇸

University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States

🇺🇸

Cleveland Clinic Cancer Center at Fairview Hospital, Cleveland, Ohio, United States

and more 10 locations

Multiple Therapies in Treating Patients With Advanced Neuroblastoma

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-03-07
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00040872
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Cisplatin, Paclitaxel, and Gemcitabine in Treating Patients With Progressive Unresectable Regional or Metastatic Bladder Cancer

Phase 2
Conditions
First Posted Date
2003-01-27
Last Posted Date
2008-07-24
Lead Sponsor
GERCOR - Multidisciplinary Oncology Cooperative Group
Registration Number
NCT00006118
Locations
🇫🇷

CHR de Grenoble - La Tronche, Grenoble, France

🇫🇷

C.H. Senlis, Senlis, France

🇫🇷

Centre Hospitalier Regional Metz Thionville, Thionville, France

and more 9 locations

Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

Phase 2
Terminated
Conditions
First Posted Date
2003-01-27
Last Posted Date
2015-06-08
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
100
Registration Number
NCT00019864
Locations
🇺🇸

Oklahoma University Cancer Institute, Oklahoma City, Oklahoma, United States

🇺🇸

Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office, Bethesda, Maryland, United States

🇺🇸

Cook Children's Medical Center - Fort Worth, Fort Worth, Texas, United States

and more 1 locations

Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2023-06-15
Lead Sponsor
Eastern Cooperative Oncology Group
Registration Number
NCT00049348
Locations
🇺🇸

Mason District Hospital, Havana, Illinois, United States

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

Hematology and Oncology Associates, Chicago, Illinois, United States

and more 134 locations

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2014-05-09
Lead Sponsor
Fox Chase Cancer Center
Target Recruit Count
21
Registration Number
NCT00021320
Locations
🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

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