Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Imatinib Mesylate and Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2008-07-24
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00045604
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-08-26
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
33
Registration Number
NCT00002854
Locations
🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-09-17
Lead Sponsor
German Hodgkin's Lymphoma Study Group
Target Recruit Count
220
Registration Number
NCT00025636
Locations
🇧🇪

Ziekenhuis Netwerk Antwerpen Middelheim, Antwerp, Belgium

🇩🇪

Universitaetsklinikum Essen, Essen, Germany

🇩🇪

Klinik Fuer Innere Medizin, Hematology/Oncology, Ernst Moritz Armdt Universitaet, Greifswald, Germany

and more 41 locations

Combination Chemotherapy in Treating Patients With Esophageal Cancer

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-12
Lead Sponsor
Medical Research Council
Target Recruit Count
1300
Registration Number
NCT00041262
Locations
🇬🇧

Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust, Birmingham, England, United Kingdom

S0122: Combination Chemotherapy, Radiation Therapy, and Vaccine Therapy in Limited-Stage Small Cell Lung Cancer

First Posted Date
2003-01-27
Last Posted Date
2012-06-13
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
9
Registration Number
NCT00045617
Locations
🇺🇸

CCOP - Columbus, Columbus, Ohio, United States

🇺🇸

Veterans Affairs Outpatient Clinic - Martinez, Martinez, California, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 97 locations

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-01-07
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
45
Registration Number
NCT00012012
Locations
🇺🇸

Cancer Treatment Center, Wooster, Ohio, United States

🇺🇸

Akron City Hospital, Akron, Ohio, United States

🇺🇸

Baptist Cancer Institute - Jacksonville, Jacksonville, Florida, United States

and more 14 locations

Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor

First Posted Date
2003-01-27
Last Posted Date
2015-12-03
Lead Sponsor
NYU Langone Health
Registration Number
NCT00003273
Locations
🇺🇸

Cancer Research Center of Hawaii, Honolulu, Hawaii, United States

🇺🇸

State University of New York Health Sciences Center - Stony Brook, Stony Brook, New York, United States

🇺🇸

Maine Children's Cancer Program, Scarborough, Maine, United States

and more 16 locations
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