Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
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For the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative.
Beijing Hui-Long Guan Hospital, Beijing, China
Baylor College of Medicine - Michael E. DeBakey VA Medical Center, Houston, Texas, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
University of Rochester Cancer Center, Rochester, New York, United States
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