Testosterone

Generic Name: Testosterone

Brand Names: Androderm, Androgel, Axiron, Fortesta, Natesto, Striant, Testim, Testopel, Vogelxo

Drug Type: Small Molecule

Chemical Formula: C_₁₉H_₂₈O_₂

CAS Number: 58-22-0

Unique Ingredient Identifier: 3XMK78S47O

Background: Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.

Testosterone was isolated from samples and also synthesized in 1935.

Indication: Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

Associated Conditions: Hypergonadotropic Hypogonadism, Hypogonadotrophic Hypogonadism, Idiopathic Hypogonadotropic Hypogonadism, Puberty, Delayed, Inoperable, metastatic Breast cancer

Associated Therapies: -

Clinical Trials

Muscle Anabolic Interventions to Accelerate Recovery From Hospitalization in Geriatric Patients

Phase 1

Completed

Conditions: Aging

Interventions: Drug: Testosterone
Other: Placebo Injection
Dietary Supplement: Protein Supplement
Other: Placebo supplement

First Posted Date: 2016-12-13

Last Posted Date: 2024-12-17

Lead Sponsor: The University of Texas Medical Branch, Galveston

Target Recruit Count: 80

Registration Number: NCT02990533

Locations: 🇺🇸
Jennie Sealy Hospital, Galveston, Texas, United States

Starting a Testosterone and Exercise Program After Hip Injury

Phase 3

Completed

Conditions: Sarcopenia
Frailty
Hip Fracture

Interventions: Drug: Testosterone
Behavioral: Home exercise program
Drug: Placebo gel
Behavioral: Supervised exercise training
Behavioral: Health Education Modules

First Posted Date: 2016-10-19

Last Posted Date: 2024-03-27

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 129

Registration Number: NCT02938923

Locations: 🇺🇸
University of Maryland School of Medicine/Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸
HebrewSenior Life Harvard Medical School, Roslindale, Massachusetts, United States
🇺🇸
Washington University School of Medicine in St. Louis, Saint Louis, Missouri, United States

and more 5 locations

Effect of PROGRESSive Training and Teststerone in Older Frail Men

Phase 2

Completed

Conditions: Muscle Weakness

Interventions: Drug: testosterone
Other: Progressive muscle training

First Posted Date: 2016-08-19

Last Posted Date: 2024-05-29

Lead Sponsor: University Hospital, Gentofte, Copenhagen

Target Recruit Count: 192

Registration Number: NCT02873559

Locations: 🇩🇰
Karsten Overgaard, Hellerup, Danmark, Denmark
🇩🇰
Medical Dept. O, Geriatric Section, Herlev, Denmark

Effect of Testosterone Replacement on Exercise Capacity in Hypogonadal Men After a Recent Myocardial Infarction

Phase 2

Withdrawn

Conditions: Hypogonadism
Acute Myocardial Infarction: Rehabilitation Phase

Interventions: Drug: Testosterone
Drug: Normal Saline

First Posted Date: 2016-06-16

Last Posted Date: 2019-11-21

Lead Sponsor: Texas Tech University Health Sciences Center

Registration Number: NCT02803073

Locations: 🇺🇸
Mission Fitness-Medical Center Hospital, Odessa, Texas, United States

A Multinomial Process Model of Moral Judgment

Phase 4

Completed

Conditions: Placebos
Testosterone

Interventions: Drug: Placebo
Drug: Testosterone

First Posted Date: 2016-06-14

Last Posted Date: 2018-11-23

Lead Sponsor: University of Texas at Austin

Target Recruit Count: 220

Registration Number: NCT02799277

Locations: 🇺🇸
University of Texas at Austin Department of Psychology, Austin, Texas, United States

Effects of Sex Steroids on the Serotonin System

Phase 4

Conditions: Gender Dysphoria

Interventions: Drug: Cyproterone Acetate
Drug: Testosterone
Drug: Lynestrenol
Drug: Estradiol
Drug: Triptorelin acetate

First Posted Date: 2016-03-22

Last Posted Date: 2018-10-15

Lead Sponsor: Medical University of Vienna

Target Recruit Count: 92

Registration Number: NCT02715232

Locations: 🇦🇹
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

Testosterone Replacement in Renal Failure

Phase 1

Terminated

Conditions: Hypogonadism

Interventions: Drug: Saline
Drug: Testosterone

First Posted Date: 2016-03-18

Last Posted Date: 2019-05-28

Lead Sponsor: Texas Tech University Health Sciences Center

Target Recruit Count: 21

Registration Number: NCT02712944

Locations: 🇺🇸
TTUHSC-Permian Basin, Odessa, Texas, United States

Cycled Testosterone Therapy to Improve Physical Function in Frail Nursing Home Residents

Early Phase 1

Terminated

Conditions: Aging

Interventions: Drug: Placebo
Drug: Testosterone

First Posted Date: 2016-02-10

Last Posted Date: 2019-02-18

Lead Sponsor: The University of Texas Medical Branch, Galveston

Target Recruit Count: 3

Registration Number: NCT02679274

Locations: 🇺🇸
Gulf Health Care Center, Texas City, Texas, United States

Intranasal Delivery of Testosterone and Its Effect on Doping Markers

Phase 4

Completed

Conditions: Abuse of Anabolic Steroids

Interventions: Drug: Testosterone

First Posted Date: 2015-11-20

Last Posted Date: 2020-02-11

Lead Sponsor: University of Utah

Target Recruit Count: 5

Registration Number: NCT02611154

Locations: 🇺🇸
University of Utah Orthopaedic Center, Salt Lake City, Utah, United States

Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes

Phase 4

Completed

Conditions: Long QT Syndrome

Interventions: Drug: Testosterone
Drug: Progesterone
Drug: Placebo
Drug: Ibutilide

First Posted Date: 2015-08-03

Last Posted Date: 2019-08-28

Lead Sponsor: Indiana University

Target Recruit Count: 14

Registration Number: NCT02513940

Locations: 🇺🇸
Indiana University, Indianapolis, Indiana, United States

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