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Testosterone

Generic Name
Testosterone
Brand Names
Androderm, Androgel, Axiron, Fortesta, Natesto, Striant, Testim, Testopel, Vogelxo
Drug Type
Small Molecule
Chemical Formula
C19H28O2
CAS Number
58-22-0
Unique Ingredient Identifier
3XMK78S47O
Background

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.

Testosterone was isolated from samples and also synthesized in 1935.

Indication

Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

Associated Conditions
Hypergonadotropic Hypogonadism, Hypogonadotrophic Hypogonadism, Idiopathic Hypogonadotropic Hypogonadism, Puberty, Delayed, Inoperable, metastatic Breast cancer

Vogelxo(R) ABPM Study in Hypogandal Men

Phase 4
Completed
Conditions
Hypogonadism, Male
Interventions
First Posted Date
2020-09-22
Last Posted Date
2024-10-18
Lead Sponsor
Upsher-Smith Laboratories
Target Recruit Count
122
Registration Number
NCT04558567
Locations
🇺🇸

Upsher-Smith Clinical Trial Site #1, Miami, Florida, United States

🇺🇸

Upsher-Smith Clinical Trials Site #8, San Antonio, Texas, United States

🇺🇸

Upsher-Smith Clinical Trial Site #2, Anaheim, California, United States

and more 4 locations

Testopel ® vs. Generic Testosterone Pellets.

First Posted Date
2020-08-21
Last Posted Date
2023-08-14
Lead Sponsor
University of Miami
Target Recruit Count
75
Registration Number
NCT04523480
Locations
🇺🇸

University of Miami, Department of Urology, Miami, Florida, United States

Gonadal Dysfunction in Male Long-term Survivors of Malignant Lymphoma; Vitality

Phase 2
Completed
Conditions
Hypogonadism
Interventions
First Posted Date
2020-07-30
Last Posted Date
2022-11-29
Lead Sponsor
Lars Møller Pedersen
Target Recruit Count
7
Registration Number
NCT04492553
Locations
🇩🇰

Herlev University Hospital, Herlev, Denmark

🇩🇰

Copenhagen University Hospital, Copenhagen, Denmark

🇩🇰

Zealand University Hospital, Roskilde, Denmark

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism

Phase 4
Completed
Conditions
Hypogonadism, Male
Hypogonadotropic Hypogonadism
Hypogonadism
Interventions
First Posted Date
2020-07-02
Last Posted Date
2025-03-14
Lead Sponsor
Endo Pharmaceuticals
Target Recruit Count
673
Registration Number
NCT04456296
Locations
🇺🇸

Endo Clinical Trial Site #22, Tucson, Arizona, United States

🇺🇸

Endo Clinical Trial Site #3, Oviedo, Florida, United States

🇺🇸

Endo Clinical Trial Site #27, Glen Burnie, Maryland, United States

and more 32 locations

A Comparison of Side Effects in Hypogonadal Men Treated With Natesto Versus Testosterone Injections

Phase 4
Completed
Conditions
Hypogonadism, Male
Interventions
First Posted Date
2020-06-19
Last Posted Date
2023-12-13
Lead Sponsor
University of Miami
Target Recruit Count
81
Registration Number
NCT04439799
Locations
🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

Effects of External Testosteron Intake on the Choroid: Enhance-depth Imaging Optical Coherence Tomography Study

Completed
Conditions
Effects of the External Testosteron Intake Over the Choroids of the Patients With Androgen Deficiency
Interventions
First Posted Date
2020-04-10
Last Posted Date
2020-04-10
Lead Sponsor
Neon Hospital
Target Recruit Count
30
Registration Number
NCT04342247
Locations
🇹🇷

Volkan YETER, Samsun, Turkey

Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.

Completed
Conditions
Dyspareunia (Female Excluding Psychogenic)
Hypoestrogenism
Arousal Disorders, Sexual
Hypoactive Sexual Desire Disorder
Menopause Related Conditions
Vulvovaginal Disease
Interventions
First Posted Date
2020-04-07
Last Posted Date
2020-04-07
Lead Sponsor
University of Florence
Target Recruit Count
81
Registration Number
NCT04336891
Locations
🇮🇹

Andrology, Women's Endocrinology and Gender Incongruence Unit, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

Hormone Secretion in Transgender Males

Phase 4
Withdrawn
Conditions
Healthy
Transgender
Interventions
First Posted Date
2020-03-25
Last Posted Date
2025-01-13
Lead Sponsor
University of California, San Diego
Target Recruit Count
40
Registration Number
NCT04321551

A Study to Evaluate Androderm®'s Effect on Blood Pressure in Adult Hypogonodal Male Participants

Phase 4
Completed
Conditions
Hypogonadism
Interventions
First Posted Date
2020-03-25
Last Posted Date
2022-07-12
Lead Sponsor
Allergan
Target Recruit Count
168
Registration Number
NCT04320745
Locations
🇺🇸

Coastal Clinical Research, LLC, An AMR Co., Mobile, Alabama, United States

🇺🇸

Regional Urology, LLC, Shreveport, Louisiana, United States

🇺🇸

Associated Urologist of North Carolina, Raleigh, North Carolina, United States

and more 37 locations

Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency

Phase 2
Recruiting
Conditions
Hypogonadism, Male
Cancer
Fatigue
Interventions
First Posted Date
2020-03-10
Last Posted Date
2025-03-11
Lead Sponsor
Seattle Institute for Biomedical and Clinical Research
Target Recruit Count
230
Registration Number
NCT04301765
Locations
🇺🇸

Georgia Cancer Center at Augusta University, Augusta, Georgia, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

🇺🇸

Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States

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