Albendazole

Generic Name: Albendazole

Brand Names: Albenza

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₅N_₃O_₂S

CAS Number: 54965-21-8

Unique Ingredient Identifier: F4216019LN

Background: A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

Indication: For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.

Associated Conditions: Hydatid disease of the Liver, Hydatid disease of the Lung, Hydatid disease of the Peritoneum, Neurocysticercosis

Associated Therapies: -

Clinical Trials

IVM Alone vs ALB + IVM Against Onchocerciasis

Phase 3

Completed

Conditions: Onchocerciasis

Interventions: Drug: Ivermectin
Drug: Albendazole

First Posted Date: 2017-08-03

Last Posted Date: 2017-08-29

Lead Sponsor: University Hospitals Cleveland Medical Center

Target Recruit Count: 272

Registration Number: NCT03238131

Locations: 🇬🇭
Committee on Human Research Publications and Ethics, Kumasi, Ashanti, Ghana

Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection

Phase 2

Completed

Conditions: Hookworm Infections

Interventions: Biological: Na-GST-1/Alhydrogel
Biological: Na-GST-1/Alhydrogel + CPG 10104
Biological: Na-GST-1/Alhydrogel + GLA-AF
Biological: Placebo
Drug: Albendazole
Other: Necator americanus Larval Inoculum

First Posted Date: 2017-06-01

Last Posted Date: 2024-07-25

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 39

Registration Number: NCT03172975

Locations: 🇺🇸
George Washington University, Washington, District of Columbia, United States

Effect of Routine Deworming on Weight of Children

Not Applicable

Completed

Conditions: Soil Transmitted Helminths

Interventions: Dietary Supplement: Calcium 400 mg + Vitamin D 2.5 mcg
Drug: Albendazole

First Posted Date: 2017-05-16

Last Posted Date: 2017-07-13

Lead Sponsor: Dow University of Health Sciences

Target Recruit Count: 300

Registration Number: NCT03155035

Locations: 🇵🇰
Dow University of Health Sciences, Karachi, Sindh, Pakistan

Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)

Not Applicable

Completed

Conditions: Pregnancy
Stunting
Nutrition Disorders
Malnutrition in Pregnancy

Interventions: Dietary Supplement: Corn-soy-blend
Dietary Supplement: Ready-to-use-supplementary food
Drug: Standard intermittent preventive treatment of malaria during pregnancy (IPTp)
Drug: Monthly intermittent preventive treatment of malaria during pregnancy (IPTp)
Other: Insecticide-treated mosquito net
Drug: Azithromycin
Drug: Albendazole
Combination Product: Bacterial vaginosis testing and treatment

First Posted Date: 2017-03-14

Last Posted Date: 2021-01-07

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 1489

Registration Number: NCT03079388

Locations: 🇸🇱
1 Moriba Street, Pujehun, Pujehun District, Sierra Leone

Intestinal Microbiome Post-Azythromycin/Albendazole Treatment

Phase 4

Withdrawn

Conditions: Helminth Infection

Interventions: Drug: Albendazole
Drug: Delayed treatment
Drug: Azithromycin

First Posted Date: 2017-01-26

Last Posted Date: 2021-06-28

Lead Sponsor: University of California, San Francisco

Registration Number: NCT03032042

Locations: 🇪🇹
The Carter Center Ethiopia, Addis Ababa, Ethiopia

Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH)

Phase 3

Active, not recruiting

Conditions: Helminthiasis
Filariasis

Interventions: Drug: Albendazole

First Posted Date: 2017-01-09

Last Posted Date: 2024-02-07

Lead Sponsor: University of Washington

Target Recruit Count: 502363

Registration Number: NCT03014167

Locations: 🇧🇯
Institut de Recherche pour le Développement, Comé, Benin
🇲🇼
London School of Hygiene and Tropical Medicine, Mangochi, Malawi
🇮🇳
Christian Medical College, Vellore, India

Lymphatic Filariasis (LF) in Ivory Coast

Not Applicable

Completed

Conditions: Lymphatic Filariasis

Interventions: Drug: Albendazole
Drug: Ivermectin
Drug: Diethylcarbamazine

First Posted Date: 2016-11-28

Last Posted Date: 2022-04-21

Lead Sponsor: University Hospitals Cleveland Medical Center

Target Recruit Count: 189

Registration Number: NCT02974049

Locations: 🇨🇮
Cote d'Ivoire, Abidjan, Côte D'Ivoire

Design and Clinical Evaluation of a School Meal With Deworming Properties

Phase 2

Completed

Conditions: Helminthiasis
Tinea Capitis
Anemia

Interventions: Dietary Supplement: uji
Dietary Supplement: Ujiplus
Drug: Albendazole

First Posted Date: 2016-03-31

Last Posted Date: 2016-09-07

Lead Sponsor: Kenya Medical Research Institute

Target Recruit Count: 326

Registration Number: NCT02725255

Effect of Hookworm Elimination and Vitamin A Intervention on Iron Status of Preschool Children in Sichuan, China

Phase 4

Completed

Conditions: Anemia
Worm Infections

Interventions: Drug: ZENTEL and Vitamin A Soft Capsules
Drug: ZENTEL

First Posted Date: 2016-02-05

Last Posted Date: 2016-02-05

Lead Sponsor: Chengdu Maternal and Children's Health Care Hospital

Target Recruit Count: 209

Registration Number: NCT02675140

Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin

Phase 4

Completed

Conditions: Chronic Periodontitis

Interventions: Procedure: Periodontal Treatment
Drug: Albendazole

First Posted Date: 2015-12-29

Last Posted Date: 2015-12-29

Lead Sponsor: Federal University of Maranhao

Target Recruit Count: 63

Registration Number: NCT02641210

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy