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Armodafinil

Generic Name
Armodafinil
Brand Names
Nuvigil
Drug Type
Small Molecule
Chemical Formula
C15H15NO2S
CAS Number
112111-43-0
Unique Ingredient Identifier
V63XWA605I

Overview

Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.

Background

Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.

Indication

用于改善与阻塞性睡眠呼吸暂停(OSA)、发作性睡病或轮班工作障碍(SWD)相关的过度嗜睡的成年患者的清醒度。亦可用于治疗注意缺陷多动障碍、慢性疲劳综合征和重度抑郁症。

Associated Conditions

  • Narcolepsy
  • Shift-work related sleep disturbance
  • Somnolence

FDA Approved Products

Armodafinil
Manufacturer:Natco Pharma USA LLC
Route:ORAL
Strength:200 mg in 1 1
Approved: 2023/12/20
NDC:69339-179
Armodafinil
Manufacturer:Aurobindo Pharma Limited
Route:ORAL
Strength:150 mg in 1 1
Approved: 2024/02/02
NDC:65862-806
Armodafinil
Manufacturer:Natco Pharma USA LLC
Route:ORAL
Strength:150 mg in 1 1
Approved: 2023/12/20
NDC:69339-178
Armodafinil
Manufacturer:Preferred Pharmaceuticals Inc.
Route:ORAL
Strength:150 mg in 1 1
Approved: 2024/02/13
NDC:68788-7880
Armodafinil
Manufacturer:Sandoz Inc
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/01/18
NDC:0781-8029

Singapore Approved Products

No Singapore products found for this drug

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