Potassium citrate
- Generic Name
- Potassium citrate
- Brand Names
- Cytra-K, Urocit-K
- Drug Type
- Small Molecule
- Chemical Formula
- C6H5K3O7
- CAS Number
- 866-84-2
- Unique Ingredient Identifier
- 86R1NVR0HW
- Background
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent.
Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis.
- Indication
For the management of renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
- Associated Conditions
- Bowel preparation therapy, Constipation, Hypocitraturic calcium oxalate nephrolithiasis, Kidney Stones, Metabolic Acidosis, Renal tubular acidosis, Uremia, Uric Acid Nephrolithiasis, Chronic metabolic acidosis
- Associated Therapies
- Laxative
Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers
- Conditions
- Uric Acid Stones
- Interventions
- First Posted Date
- 2024-03-28
- Last Posted Date
- 2025-01-27
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 100
- Registration Number
- NCT06335537
- Locations
- 🇺🇸
University of California, Irvine Medical Center, Orange, California, United States
Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
- Conditions
- Calcium Phosphate Kidney Stones
- Interventions
- Dietary Supplement: OHCit- low doseDrug: PlaceboDietary Supplement: OHCit- standard dose
- First Posted Date
- 2023-08-21
- Last Posted Date
- 2025-04-06
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 25
- Registration Number
- NCT06003348
- Locations
- 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States
Potassium Citrate and Crystal Light Lemonade
- Conditions
- Kidney Stone
- Interventions
- First Posted Date
- 2022-05-25
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 10
- Registration Number
- NCT05389995
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet
- Conditions
- Kidney Stone
- Interventions
- Dietary Supplement: LitholyteDietary Supplement: Crystal Lite
- First Posted Date
- 2020-12-03
- Last Posted Date
- 2025-05-09
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 15
- Registration Number
- NCT04651088
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Study Evaluating Patients With Cystinuria and Efficacy and Safety Exploratory Study in the Youngest Children
- First Posted Date
- 2019-11-01
- Last Posted Date
- 2023-05-09
- Lead Sponsor
- Advicenne Pharma
- Target Recruit Count
- 72
- Registration Number
- NCT04147871
- Locations
- 🇫🇷
CHU Grenoble, Grenoble Cedex, France
🇫🇷Centre Hospitalier Universitaire de Lyon - Hôpital Femme Mère Enfant, Bron, France
🇫🇷CHU Purpan, Toulouse cedex 9, France
Study Evaluating Patients With Cystinuria
- First Posted Date
- 2019-10-24
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- Advicenne Pharma
- Registration Number
- NCT04137978
- Locations
- 🇫🇷
CHU Reims, Reims, France
🇧🇪UZ Leuven, Gasthuisberg Hospital, Leuven, Belgium
🇫🇷CHU de Bordeaux - Hôpital Pellegrin, Bordeaux, France
Extension Study in Primary Distal Renal Tubular Acidosis
- First Posted Date
- 2019-02-05
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- Advicenne Pharma
- Registration Number
- NCT03831152
- Locations
- 🇺🇸
University of South Florida Pediatric Infectious Diseases, Tampa, Florida, United States
Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure
- Conditions
- Hypertension
- Interventions
- Behavioral: Dietary Counselling
- First Posted Date
- 2019-01-18
- Last Posted Date
- 2025-04-09
- Lead Sponsor
- Ottawa Hospital Research Institute
- Target Recruit Count
- 7
- Registration Number
- NCT03809884
- Locations
- 🇨🇦
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Study Evaluating Subjects With Distal Renal Tubular Acidosis
- First Posted Date
- 2018-08-23
- Last Posted Date
- 2024-03-22
- Lead Sponsor
- Advicenne Pharma
- Target Recruit Count
- 3
- Registration Number
- NCT03644706
- Locations
- 🇺🇸
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇨🇦The Hospital for Sick Children, Toronto, Ontario, Canada
🇺🇸Children's Hospital Colorado, Aurora, Colorado, United States
Study to Assess the Efficacy and Safety of Oral Potassium Citrate on the Prevention of Nephrocalcinosis in Extreme Premature
- First Posted Date
- 2012-12-27
- Last Posted Date
- 2012-12-27
- Lead Sponsor
- Juan A. Arnaiz
- Target Recruit Count
- 74
- Registration Number
- NCT01756547
- Locations
- 🇪🇸
Hospital Clínic de Barcelona, Barcelona, Spain
Drug Development Updates
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