Amoxicillin
- Generic Name
- Amoxicillin
- Brand Names
- Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
- Drug Type
- Small Molecule
- Chemical Formula
- C16H19N3O5S
- CAS Number
- 26787-78-0
- Unique Ingredient Identifier
- 9EM05410Q9
- Background
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.
Amoxicillin was granted FDA approval on 18 January 1974.
- Indication
Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin s...
- Associated Conditions
- Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections
- Associated Therapies
- -
Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia
- Conditions
- Interventions
- First Posted Date
- 2020-04-17
- Last Posted Date
- 2020-04-17
- Lead Sponsor
- Medical University of Lodz
- Target Recruit Count
- 152
- Registration Number
- NCT04352062
- Locations
- 🇵🇱
Department of Clinical Nutrition and Gastroenterological Diagnostics Medical University of Lodz, Łódź, Poland
A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection
- Conditions
- Interventions
- First Posted Date
- 2019-12-13
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- Takeda
- Target Recruit Count
- 510
- Registration Number
- NCT04198363
- Locations
- 🇨🇳
The First People's Hospital of Foshan, Foshan, Guangdong, China
🇨🇳Friendship Hospital, Capital Medical University, Beijing, Beijing, China
🇨🇳Peking University Third Hospital, Beijing, Beijing, China
Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection
- Conditions
- Interventions
- First Posted Date
- 2019-11-19
- Last Posted Date
- 2022-04-05
- Lead Sponsor
- Phathom Pharmaceuticals, Inc.
- Target Recruit Count
- 1046
- Registration Number
- NCT04167670
- Locations
- 🇺🇸
Carolina Research, Greenville, North Carolina, United States
🇺🇸Synexus Clinical Research US, Inc. - Anderson, Anderson, South Carolina, United States
🇺🇸Anaheim Clinical Trials LLC, Anaheim, California, United States
Effects of Phenoximethylpenicillin, Amoxicillin and Amoxicillin-clavulanic Acid on the Gut Microbiota
- Conditions
- Interventions
- First Posted Date
- 2019-09-10
- Last Posted Date
- 2022-12-02
- Lead Sponsor
- Uppsala University
- Target Recruit Count
- 104
- Registration Number
- NCT04084106
- Locations
- 🇸🇪
Uppsala University Hospital, Uppsala, Sweden
Plasma Concentrations of Amoxicillin Administered in High-doses During the First Week of Treatment (MAX-AMOX)
- First Posted Date
- 2019-08-28
- Last Posted Date
- 2020-06-11
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Target Recruit Count
- 100
- Registration Number
- NCT04070469
- Locations
- 🇫🇷
CHU Clermont-Ferrand, Clermont-Ferrand, France
Immediate Versus Delayed Treatment of Odontogenic Infections
- Conditions
- Interventions
- First Posted Date
- 2019-08-14
- Last Posted Date
- 2020-10-06
- Lead Sponsor
- Boston Children's Hospital
- Registration Number
- NCT04057014
High Dose of Dual Therapy Plus Metronidazole for Helicobacter Pylori RescueTreatment
- Conditions
- Interventions
- First Posted Date
- 2019-07-18
- Last Posted Date
- 2021-09-28
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 306
- Registration Number
- NCT04024527
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Dexlansoprazole MR-Based Concomitant Quadruple Therapy
- Conditions
- Interventions
- First Posted Date
- 2019-02-04
- Last Posted Date
- 2019-05-14
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 202
- Registration Number
- NCT03829150
- Locations
- 🇨🇳
Kaohsiung Chang Gung Memorial Hospital,Taiwan, Kaohsiung, Taiwan
Comparative Efficacy of Single-dose Doxycycline Versus Standard 5- Day Amoxicillin Treatment
- First Posted Date
- 2018-12-05
- Last Posted Date
- 2018-12-05
- Lead Sponsor
- Institut de Recherche pour le Developpement
- Target Recruit Count
- 274
- Registration Number
- NCT03765931
- Locations
- 🇸🇳
Niakhar observational site, Niakhar, Fatick, Senegal
Systemic and Local Antimicrobials in the Management of Dental Abscess in Children
- Conditions
- Interventions
- First Posted Date
- 2018-12-03
- Last Posted Date
- 2020-05-12
- Lead Sponsor
- University of Malaya
- Target Recruit Count
- 55
- Registration Number
- NCT03761264
- Locations
- 🇲🇾
University of Malaya, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia
Drug Development Updates
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