Cromoglicic acid

Generic Name
Cromoglicic acid
Brand Names
Gastrocrom, Nalcrom, Nasalcrom
Drug Type
Small Molecule
Chemical Formula
C23H16O11
CAS Number
16110-51-3
Unique Ingredient Identifier
Y0TK0FS77W
Background

A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.

Indication

For the management of patients with bronchial asthma. Also used in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.

Associated Conditions
Asthma, Conjunctivitis, Vernal, Exercise-Induced Bronchospasm, Food Allergy, Keratoconjunctivitis, Perennial Allergic Rhinitis (PAR), Seasonal Allergic Conjunctivitis, Seasonal Allergic Rhinitis, Urticaria Pigmentosa, Vernal Keratoconjunctivitis
Associated Therapies
-

Cromolyn Sodium for Treatment of COVID-19 Pneumonia

First Posted Date
2021-10-14
Last Posted Date
2024-11-18
Lead Sponsor
Texas Tech University Health Sciences Center, El Paso
Target Recruit Count
22
Registration Number
NCT05077917
Locations
🇺🇸

University Medical Center of El Paso, EL Paso, Texas, United States

Influence of Cromones on Eucapnic Hyperventilation (EVH)-Test in Young (Elite) Athletes Who Tested Positive for EIB.

First Posted Date
2020-05-29
Last Posted Date
2023-08-03
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
8
Registration Number
NCT04408664
Locations
🇧🇪

AZ Maria Middelares, Ghent, Belgium

🇧🇪

UZ Leuven, Leuven, Vlaams-Brabant, Belgium

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

First Posted Date
2019-01-04
Last Posted Date
2024-10-18
Lead Sponsor
Vishwajit Nimgaonkar, MD PhD
Target Recruit Count
160
Registration Number
NCT03794076
Locations
🇺🇸

University of Pittsburgh, Pittsburgh, Pennsylvania, United States

Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction

First Posted Date
2017-05-25
Last Posted Date
2024-12-18
Lead Sponsor
Northwestern University
Target Recruit Count
20
Registration Number
NCT03167216
Locations
🇺🇸

Northwestern Medical Faculty Foundation, Chicago, Illinois, United States

Mast Cells in Acid-induced Intestinal Permeability

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2016-01-26
Last Posted Date
2024-07-10
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
20
Registration Number
NCT02664051
Locations
🇧🇪

Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven Campus Gasthuisberg O&N1, Leuven, Vlaams Brabant, Belgium

Effect of Pre-Treatment With Cromolyn or Albuterol on Response to PUL-042 Inhalation Solution (PUL-042)

First Posted Date
2015-10-02
Last Posted Date
2017-08-10
Lead Sponsor
Pulmotect, Inc.
Target Recruit Count
16
Registration Number
NCT02566252
Locations
🇺🇸

WCCT Global, Cypress, California, United States

An Analysis of the Effect of Topical Cromolyn Sodium on Rosacea-associated Erythema

First Posted Date
2013-09-02
Last Posted Date
2019-08-07
Lead Sponsor
University of California, San Diego
Target Recruit Count
10
Registration Number
NCT01933464
Locations
🇺🇸

UCSD Division of Dermatology, San Diego, California, United States

Cromolyn Detection of Silent Aspiration

First Posted Date
2013-04-26
Last Posted Date
2019-02-15
Lead Sponsor
University of California, San Francisco
Target Recruit Count
16
Registration Number
NCT01841307
Locations
🇺🇸

UCSF Airway Clinical Research Center, San Francisco, California, United States

Cromoglicate in Psoriasis

Phase 2
Completed
Conditions
Interventions
First Posted Date
2012-11-07
Last Posted Date
2022-05-04
Lead Sponsor
LEO Pharma
Target Recruit Count
30
Registration Number
NCT01722812
Locations
🇩🇪

Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany

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