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Ropivacaine

Generic Name
Ropivacaine
Brand Names
Naropin
Drug Type
Small Molecule
Chemical Formula
C17H26N2O
CAS Number
84057-95-4
Unique Ingredient Identifier
7IO5LYA57N
Background

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication

Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions
Acute Pain, Postoperative pain
Associated Therapies
Surgical anesthesia therapy
Clinical Trials
Related News

Efficacy of Continuous Infusion Ropivacaine Interscalene Blocks

Phase 4
Completed
Conditions
Full-thickness Rotator Cuff Tear
Interventions
Procedure: Arthroscopic Rotator Cuff Repair
Drug: Saline
Drug: Ropivacaine
First Posted Date
2015-06-04
Last Posted Date
2020-12-22
Lead Sponsor
Orlando Health, Inc.
Target Recruit Count
51
Registration Number
NCT02462382
Locations
🇺🇸

Orlando Orthopaedic Center, Orlando, Florida, United States

The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:

Not Applicable
Completed
Conditions
Chronic Pain
Acute Pain
Interventions
Procedure: intravenous Patient controlled analgesia
Procedure: Tap block
Drug: Morphine
Drug: Ropivacaine
First Posted Date
2015-06-02
Last Posted Date
2018-02-05
Lead Sponsor
Regina Elena Cancer Institute
Target Recruit Count
96
Registration Number
NCT02460640
Locations
🇮🇹

Regina Elena CI, Rome, Italy

The Effect of the Serratus Block on Pain Control After Breast Surgery

Phase 2
Completed
Conditions
Anesthesia
Interventions
Procedure: Serratus Block
Procedure: Placebo Block
Other: sterile saline
Drug: ropivacaine
Drug: epinephrine
First Posted Date
2015-05-25
Last Posted Date
2020-01-13
Lead Sponsor
Women's College Hospital
Target Recruit Count
40
Registration Number
NCT02453516
Locations
🇨🇦

Women's College Hospital, Toronto, Ontario, Canada

Ultrasound-guided Bilateral Rectus Sheath Block for Robotic Single-port Gynecologic Surgery

Not Applicable
Completed
Conditions
Gynecologic Disease
Interventions
Procedure: Rectus sheath block
Drug: Ropivacaine
Other: Bandage
Drug: IV-PCA containing Fentanyl
First Posted Date
2015-05-21
Last Posted Date
2017-02-08
Lead Sponsor
Ewha Womans University Mokdong Hospital
Target Recruit Count
60
Registration Number
NCT02450084
Locations
🇰🇷

Ewha Womans University Mokdong Hospital, Seoul, Korea, Republic of

Ropivacaine After Sternotomy

Phase 4
Completed
Conditions
Postoperative Pain
Interventions
Drug: Ropivacaine
First Posted Date
2015-05-20
Last Posted Date
2018-04-24
Lead Sponsor
Kuopio University Hospital
Target Recruit Count
90
Registration Number
NCT02449486
Locations
🇫🇮

Kuopio University hospital, Kuopio, Finland

Intraperitoneal Local Anaesthetic in Bowel Surgery

Phase 4
Completed
Conditions
Colorectal Disorders
Interventions
Drug: 0.9% Saline
Drug: Ropivacaine
First Posted Date
2015-05-20
Last Posted Date
2017-03-27
Lead Sponsor
Royal Adelaide Hospital
Target Recruit Count
86
Registration Number
NCT02449720
Locations
🇦🇺

Royal Adelaide Hospital, Adelaide, South Australia, Australia

Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain After Surgery in Patients With Bladder Cancer

Phase 3
Withdrawn
Conditions
Bladder Carcinoma
Post-operative Pain
Interventions
Other: Placebo
Drug: Ropivacaine Hydrochloride
Other: Questionnaire Administration
First Posted Date
2015-05-08
Last Posted Date
2019-04-16
Lead Sponsor
University of Southern California
Registration Number
NCT02438852
Locations
🇺🇸

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

Ropivacaine With Clonidine For Pediatric Rectus Sheath Blocks- The Magic Combination

Not Applicable
Terminated
Conditions
Postoperative Pain
Interventions
Drug: Clonidine
Drug: Ropivacaine
First Posted Date
2015-05-08
Last Posted Date
2019-07-23
Lead Sponsor
Mihaela Visoiu
Target Recruit Count
50
Registration Number
NCT02439281
Locations
🇺🇸

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States

Low Dose IV Dexamethasone in Prolonging Caudal Anesthesia in Children Undergoing Genitourinary Surgery

Phase 4
Terminated
Conditions
Surgery
Interventions
Drug: Ropivacaine
Drug: Dexamethasone
First Posted Date
2015-05-06
Last Posted Date
2021-05-07
Lead Sponsor
Indiana University
Target Recruit Count
8
Registration Number
NCT02436265
Locations
🇺🇸

Riley Hospital for Children, Indianapolis, Indiana, United States

Ultrasonography-guided and Surgical Rectus Sheath Block in Single-port Access Laparoscopy

Phase 2
Conditions
Pain
Interventions
Procedure: Rectus sheath block
Other: Normal saline
Drug: Ropivacaine
First Posted Date
2015-04-30
Last Posted Date
2015-05-04
Lead Sponsor
Chungnam National University Hospital
Target Recruit Count
30
Registration Number
NCT02431065
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