Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Bilateral Dual Transversus Abdominis Plane Block for Robotic Assisted Laparoscopic Surgery

Not Applicable

Terminated

Conditions: Robotic Assisted Laparoscopic Surgery
Bilateral Dual Transversus Abdominis Plane Block
Pain Treatment

Interventions: Drug: Isotonic potassium chloride
Drug: Ropivacaine

First Posted Date: 2013-01-04

Last Posted Date: 2015-05-12

Lead Sponsor: Aalborg University Hospital

Target Recruit Count: 80

Registration Number: NCT01760161

Locations: 🇩🇰
Aalborg Hospital, Aalborg, Region Nord, Denmark

Continuous Wound Infusion in Lumbar or Thoracic Surgery

Phase 2

Completed

Conditions: Lumbar Spine Surgery
Thoracic Spine Surgery

Interventions: Drug: Ropivacaine
Drug: Saline solution 0.9%

First Posted Date: 2012-12-06

Last Posted Date: 2012-12-06

Lead Sponsor: University Hospital, Grenoble

Target Recruit Count: 60

Registration Number: NCT01743794

Locations: 🇫🇷
University Hospital, Departement of Anesthesia and Intensive Care, Grenoble, Rhone Alpes, France

Pain Treatment After TKA With LIA and Intra-articular Continuous Infusion Pump

Phase 4

Completed

Conditions: Postoperative Pain Management

Interventions: Drug: Placebo
Drug: Ropivacaine

First Posted Date: 2012-11-15

Last Posted Date: 2014-11-26

Lead Sponsor: Region Skane

Target Recruit Count: 200

Registration Number: NCT01726686

Locations: 🇸🇪
Department of Orthopedics, Skane University Hospital, Lund University, Lund, Sweden

Evaluation of Block Duration in Type 2 Diabetes Patients

Phase 4

Completed

Conditions: Diabetes Type 2

Interventions: Drug: ropivacaine

First Posted Date: 2012-10-11

Last Posted Date: 2012-12-24

Lead Sponsor: Pierre and Marie Curie University

Target Recruit Count: 70

Registration Number: NCT01704612

Locations: 🇫🇷
APHP Pitié-Sampetriere, Paris, France

Epidural Analgesia and Troubles of Fetal Cardiaq Rythm : Effect of the Systemic Transfer of Ropivacaine and Sufentanil

Phase 4

Completed

Conditions: Fetal Cardiac Rhythm Abnormalities

Interventions: Drug: ropivacaine

First Posted Date: 2012-09-18

Last Posted Date: 2016-01-25

Lead Sponsor: University Hospital, Rouen

Target Recruit Count: 40

Registration Number: NCT01686347

Locations: 🇫🇷
centre hospitalier universitaire de Rouen, Hopital Charles Nicolle, Rouen, France

A Study Investigating Properties of the Transversus Abdominis Plane Block

Not Applicable

Completed

Conditions: Anesthesia, Local

Interventions: Drug: Ropivacaine

First Posted Date: 2012-09-06

Last Posted Date: 2015-03-20

Lead Sponsor: Hillerod Hospital, Denmark

Target Recruit Count: 16

Registration Number: NCT01679392

Locations: 🇩🇰
Hillerød Hospital, Hillerød, Denmark

Intraperitoneal Atomization of Ropivacaine During Gynecologic Laparoscopic Surgery

Phase 3

Conditions: Postoperative Pain

Interventions: Drug: placebo (normal saline)
Drug: Ropivacaine

First Posted Date: 2012-06-20

Last Posted Date: 2012-06-20

Lead Sponsor: University of Padova

Target Recruit Count: 200

Registration Number: NCT01623635

Locations: 🇮🇹
Azienda Ospedaliera-Università Padova, Padova, Italy

Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study

Not Applicable

Completed

Conditions: Total Knee Replacement
Primary Knee Arthroplasty

Interventions: Drug: Ropivacaine
Drug: Fentanyl

First Posted Date: 2012-06-15

Last Posted Date: 2013-11-11

Lead Sponsor: University of South Florida

Target Recruit Count: 60

Registration Number: NCT01620047

Locations: 🇺🇸
Tampa General Hospital, Tampa, Florida, United States

A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block

Phase 4

Terminated

Conditions: Fracture of Foot

Interventions: Drug: Bupivacaine
Drug: Ropivacaine

First Posted Date: 2012-06-11

Last Posted Date: 2016-08-01

Lead Sponsor: Northwestern University

Target Recruit Count: 17

Registration Number: NCT01615939

Locations: 🇺🇸
Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

Is Regional Anesthesia of the Hip Preferable Over Traditional Analgesia in the Acute Stage of the Management of Patients With a Fracture of the Hip

Phase 4

Terminated

Conditions: Hip Fractures

Interventions: Drug: Natrium chloride
Drug: Ropivacaine

First Posted Date: 2012-05-08

Last Posted Date: 2015-04-21

Lead Sponsor: Landstinget i Värmland

Target Recruit Count: 37

Registration Number: NCT01593319

Locations: 🇸🇪
Ortopedkliniken, Centralsjukhuset i Karlstad, Karlstad, Värmland, Sweden

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