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Ropivacaine

Generic Name
Ropivacaine
Brand Names
Naropin
Drug Type
Small Molecule
Chemical Formula
C17H26N2O
CAS Number
84057-95-4
Unique Ingredient Identifier
7IO5LYA57N
Background

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication

Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions
Acute Pain, Postoperative pain
Associated Therapies
Surgical anesthesia therapy
Clinical Trials
Related News

Cardiovascular Safety Research: Bupivacaine With Vasoconstrictor Versus Ropivacaine in Brachial Plexus Block

Phase 4
Conditions
Injuries, Hand
Anesthesia Conduction
Anesthetics, Local
Interventions
Drug: Bupivacaine
Drug: Ropivacaine
First Posted Date
2007-08-31
Last Posted Date
2009-02-19
Lead Sponsor
University of Sao Paulo
Target Recruit Count
48
Registration Number
NCT00523289

Interscalene Nerve Blocks With Ropivacaine Alone, With Dexamethasone, Plus Systemic Dexamethasone

Not Applicable
Terminated
Conditions
Pain
Interventions
Drug: Ropivacaine
Drug: dex
Drug: Saline
Drug: Bupivacaine
First Posted Date
2007-08-22
Last Posted Date
2017-07-21
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
218
Registration Number
NCT00519584
Locations
🇺🇸

Cleveland Clinic Hillcrest, Cleveland, Ohio, United States

🇺🇸

Cleveland Clinic /Euclid Hospital, Euclid, Ohio, United States

Pain Relief by Intra-Peritoneal Ropivacaine During Gynecological Laparoscopy

Phase 3
Completed
Conditions
Laparoscopic Surgical Procedures
Interventions
Device: Aeroneb Pro Nezulizer, Aerogen, Ireland
Drug: ropivacaine
First Posted Date
2007-02-09
Last Posted Date
2008-06-20
Lead Sponsor
Carmel Medical Center
Target Recruit Count
40
Registration Number
NCT00433316
Locations
🇮🇱

the Carmel Medical Center Ambulatory Gynecoendoscopic Unit, Haifa, Israel

Ropivacaine Versus Bupivacaine for Spinal Anaesthesia in Patients Undergoing Unilateral Lower Limb Surgery

Phase 3
Completed
Conditions
Anesthesia,Spinal
First Posted Date
2006-07-31
Last Posted Date
2009-03-26
Lead Sponsor
AstraZeneca
Target Recruit Count
220
Registration Number
NCT00358280
Locations
🇨🇳

Research Site, Xi'an, China

Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer

Completed
Conditions
Fallopian Tube Cancer
Pain
Cervical Cancer
Endometrial Cancer
Ovarian Cancer
Perioperative/Postoperative Complications
Sarcoma
Interventions
Drug: hydromorphone hydrochloride
Drug: fentanyl citrate
Drug: ropivacaine hydrochloride
First Posted Date
2006-02-24
Last Posted Date
2014-05-20
Lead Sponsor
University of California, San Francisco
Target Recruit Count
240
Registration Number
NCT00295945
Locations
🇺🇸

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States

Analgesic Efficacy of Inter Pleural Ropivacaine Road in Post Thoracotomy Pain for Oncologic Surgery

Phase 2
Completed
Conditions
Postoperative Pain
Cancer
Interventions
Drug: Ropivacaine
First Posted Date
2005-09-21
Last Posted Date
2015-11-26
Lead Sponsor
Institut Bergonié
Target Recruit Count
90
Registration Number
NCT00210132
Locations
🇫🇷

Institut Bergonié - Centre Régional de Luttre Contre le Cancer de Bordeaux et du Sud Ouest, Bordeaux, France

Evaluation of Efficacy of Lumbar Plexus Bloc After Hip Surgery

Not Applicable
Completed
Conditions
Postoperative
Pain
First Posted Date
2005-09-08
Last Posted Date
2017-11-01
Lead Sponsor
University Hospital, Angers
Target Recruit Count
60
Registration Number
NCT00150865
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